Home Chemistry Organic Building Blocks Bromides 2-Bromo-6-Fluorophenol
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—OH,—F).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Fries Rearrangement: Phenol can undergo the Fries rearrangement when treated with a Lewis acid catalyst, leading to the migration of an acyl group within the molecule.
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
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Methyl 4-bromo-2-fluoro-3-hydroxybenzoate
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