Home Chemistry Heterocyclic Building Blocks Pyridines 6-Methylnicotinonitrile
Nucleophilic Substitution: The nitrile group can undergo nucleophilic substitution reactions, where the cyanide ion can be replaced by a nucleophile, such as a Grignard reagent or an amine.
Acid-Base Reactions: The pyridine ring can undergo acid-base reactions due to the presence of the nitrogen atom. It can act as a base, accepting a proton from an acid, or as an acid, donating a proton to a base.
Reduction: The nitrile group can be reduced to an amine using reducing agents like lithium aluminum hydride (LiAlH4) or hydrogen gas in the presence of a metal catalyst.
Acylation: The pyridine ring can undergo acylation reactions, where an acyl group is added to the nitrogen atom. This reaction can be catalyzed by Lewis acids or acyl chlorides.
Halogenation: The methyl group can undergo halogenation reactions, where one or more hydrogen atoms are replaced by halogen atoms like chlorine or bromine.
Oxidation: Both the methyl group and the nitrile group can undergo oxidation reactions under appropriate conditions to form various functional groups.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
click to sign in and save
6-Methyl-4-(trifluoromethyl)nicotinonitrile
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :