Home Chemistry Organic Building Blocks Nitroes 1-Methyl-4-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —NO2,—CH3).
Nitration: Nitrobenzene can undergo nitration reactions, where a nitro group (-NO2) is introduced onto the benzene ring. This is typically achieved by treating nitrobenzene with a mixture of concentrated sulfuric acid and concentrated nitric acid.
Alkylation: Similar to acylation, toluene can also undergo Friedel-Crafts alkylation reactions, where an alkyl group is introduced onto the benzene ring. Alkylation reactions also require a Lewis acid catalyst.
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1-Methyl-4-nitro-2-(trifluoromethyl)benzene
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1-Bromo-4-iodo-5-methyl-2-nitrobenzene
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1-Fluoro-3-methoxy-5-methyl-2-nitrobenzene
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4-Methyl-1-nitro-2-(trifluoromethyl)benzene
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