Home Chemistry Heterocyclic Building Blocks Piperidines Phenyl(Piperidin-4-Yl)Methanone
Reduction: The carbonyl group in the compound can be reduced to the corresponding alcohol using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
Grignard Reaction: Phenyl(piperidin-4-yl)methanone can react with a Grignard reagent (e.g., phenylmagnesium bromide) to form tertiary alcohols or undergo further reactions to produce more complex compounds.
Amination: The compound can undergo amination reactions where the carbonyl group is converted into an amine group. This can be achieved using reagents like ammonia or primary amines in the presence of reducing agents.
Cannizzaro Reaction: Under certain conditions, especially with strong bases, aromatic ketones like this one can undergo a Cannizzaro reaction, which involves self-disproportionation to form a corresponding alcohol and carboxylic acid.
Friedel-Crafts Acylation: It can participate in Friedel-Crafts acylation reactions with Lewis acids like aluminum chloride (AlCl3), leading to the introduction of an acyl group onto an aromatic ring.
Reductive Amination: If reacted with a primary amine and a reducing agent, it can undergo reductive amination, leading to the formation of secondary and tertiary amines.
Oxidation: The compound can undergo oxidation reactions, converting the carbonyl group into a carboxylic acid or other oxidized products, depending on the reaction conditions and reagents used.
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tert-Butyl 4-(3-(trifluoromethyl)benzoyl)piperidine-1-carboxylate
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(4-Bromophenyl)(4-piperidyl)methanone Hydrochloride
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1-(4-(2,4-Difluorobenzoyl)piperidin-1-yl)ethanone
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tert-Butyl 4-benzoylpiperidine-1-carboxylate
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tert-Butyl 4-(2-fluorobenzoyl)piperidine-1-carboxylate
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tert-Butyl 4-(2,4-difluorobenzoyl)piperidine-1-carboxylate
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tert-Butyl 4-(4-fluorobenzoyl)piperidine-1-carboxylate
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tert-Butyl 4-(4-methylbenzoyl)piperidine-1-carboxylate
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tert-Butyl 4-(4-bromo-2-fluorobenzoyl)piperidine-1-carboxylate
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tert-Butyl 4-(5-chloro-2-fluorobenzoyl)piperidine-1-carboxylate
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4-(3-Chlorobenzoyl)piperidine Hydrochloride
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4-(4-Methoxybenzoyl)piperidine hydrochloride
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tert-Butyl 4-(4-methoxybenzoyl)piperidine-1-carboxylate
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(4-Chlorophenyl)(piperidin-4-yl)methanone hydrochloride
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