Home Chemistry Heterocyclic Building Blocks Indazoles 5-Methoxy-1H-Indazole
Substitution Reactions: The methoxy group can undergo substitution reactions with various electrophiles, leading to the formation of substituted methoxyindazoles.
Nucleophilic Addition: The electron-rich indazole ring can undergo nucleophilic addition reactions with electrophiles, such as alkyl halides or acyl chlorides.
Ring-Opening Reactions: The indazole ring may undergo ring-opening reactions under certain conditions, leading to the formation of open-chain compounds.
Oxidation: The indazole ring can be oxidized to form various oxidation products, such as N-oxides or oxindoles.
Reduction: The indazole ring can be reduced to form the corresponding dihydroindazole or tetrahydroindazole derivatives using reducing agents such as hydrogen gas over a metal catalyst or sodium borohydride.
Cyclization Reactions: It can undergo cyclization reactions with appropriate reagents to form fused ring systems or heterocyclic compounds.
Acylation: The nitrogen atom in the indazole ring can undergo acylation reactions to form N-acyl derivatives.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
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Ethyl 5-methoxy-1H-indazole-3-carboxylate
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