Home Chemistry Heterocyclic Building Blocks Pyridines 2,6-Dichloro-4-Iodopyridine
Substitution Reactions: The halogens (chlorine and iodine) can be substituted with other functional groups such as alkyl or aryl groups. This could involve reactions like nucleophilic substitution or metal-catalyzed cross-coupling reactions.
Redox Reactions: The iodine atom, being more reactive than the chlorine atoms, can undergo redox reactions. It can be oxidized to iodine derivatives or reduced to iodide ions, depending on the reaction conditions and the presence of suitable reagents.
Palladium-Catalyzed Reactions: Palladium-catalyzed reactions, such as Suzuki-Miyaura coupling or Heck reaction, can occur where the iodine atom acts as a site for coupling with another organic moiety.
Nucleophilic Aromatic Substitution (S[sub]N[/sub]Ar): The pyridine ring can undergo nucleophilic aromatic substitution reactions, particularly if there are electron-donating or electron-withdrawing groups present in the molecule.
Metal Complexation: The presence of both chlorine and iodine atoms can make the molecule suitable for coordination with transition metals, leading to the formation of metal complexes with potential applications in catalysis or materials science.
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Methyl 2,6-dichloro-4-iodonicotinate
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