Home Life Science Amino Acids Amino Acid Derivatives (9H-Fluoren-9-Yl)Methyl (2-(Thiophen-2-Yl)Ethyl)Carbamate
Reductive Amination: The primary amine group (methylamine) produced through hydrolysis can participate in reductive amination reactions. It can react with various carbonyl compounds (aldehydes or ketones) in the presence of a reducing agent like sodium cyanoborohydride to form secondary or tertiary amines.
Esterification: The alcohol group (2-(thiophen-2-yl)ethanol) can be subjected to esterification reactions with carboxylic acids in the presence of acid and a dehydrating agent to form esters.
Oxidation: The thiophene ring can be oxidized under appropriate conditions to form thiophene derivatives with higher oxidation states.
Substitution Reactions: The aromatic ring (9H-fluoren-9-yl) can undergo electrophilic aromatic substitution reactions, such as halogenation, nitration, sulfonation, or Friedel-Crafts reactions, depending on the reagents and conditions applied.
Reduction: The carbamate functional group can be reduced to the corresponding amine using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Amide Formation: The primary amine group can react with carboxylic acids to form amides.
Coupling Reactions: The compound can participate in various coupling reactions, such as Suzuki coupling, Heck coupling, or Sonogashira coupling, depending on the substituents and reaction conditions.
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Chiral optical isomerism+−
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Fmoc-(R)-3-Amino-4-(2-thienyl)-butyricacid
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Fmoc-(S)-3-Amino-4-(2-thienyl)-butyric acid
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