Home Chemistry Organic Building Blocks Isocyanates and Isothiocyanates Isothiocyanatobenzene
These compounds have the same murcko framework: benzene,and at least 1 kind of functional groups( —N=C=S).
Multicomponent Reaction: Isothiocyanatobenzene can participate in the Ugi reaction, a multicomponent reaction involving an 【isocyanide|https://www.ambeed.com/isocyanides.html】, an 【aldehyde|https://www.ambeed.com/aldehydes.html】 or 【ketone|https://www.ambeed.com/ketones.html】, an 【amine|https://www.ambeed.com/amines.html】, and a 【carboxylic acid|https://www.ambeed.com/carboxylic-acids.html】. This reaction forms a product known as a Ugi adduct.
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3,5-Bis(trifluoromethyl)phenyl isothiocyanate
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4-Isothiocyanato-2-(trifluoromethyl)benzonitrile
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1-Fluoro-3-isothiocyanato-5-methylbenzene
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1,3,5-Trifluoro-2-isothiocyanatobenzene
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