Home Chemistry Organic Building Blocks Fluorinated Building Blocks (2-Fluorophenyl)Methanol
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH2OH).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Hydrogenolysis: Phenylmethanol can be cleaved using hydrogen gas and a catalyst to form benzene and methanol.
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2,3,5,6-Tetrafluoro-1,4-benzenedimethanol
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(4-Chloro-2-fluoro-6-methoxyphenyl)methanol
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(2,6-Difluoro-3,5-dimethoxyphenyl)methanol
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(2,3,5,6-Tetrafluoro-4-(methoxymethyl)phenyl)methanol
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(2-Fluoro-3-(hydroxymethyl)phenyl)boronic acid
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(2,3-Difluoro-4-methoxyphenyl)methanol
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(4-Bromo-2-fluoro-6-methylphenyl)methanol
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