Home Chemistry Organic Building Blocks Chlorides 2-Chloro-4-Fluoroaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—NH2,—F).
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Oxidation: Aniline can be oxidized to form quinone and other oxidation products using strong oxidizing agents.
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
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Methyl 2-amino-3-chloro-5-fluorobenzoate
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(2-Amino-3-chloro-5-fluorophenyl)methanol
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