Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1-Fluoro-4-Methylbenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH3).
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Sulfonation: Toluene can be sulfonated, leading to the introduction of a sulfonic acid group (-SO3H) onto the benzene ring. This is often carried out using concentrated sulfuric acid.
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5-Fluoro-2-methylphenylhydrazine hydrochloride
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1-(5-Fluoro-2-methylphenyl)ethan-1-amine hydrochloride
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(S)-1-(5-Fluoro-2-methylphenyl)ethanamine hydrochloride
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