Home Chemistry Organic Building Blocks Iodides 1-Iodo-3-(Trifluoromethoxy)Benzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—OCF3).
Sandmeyer Reaction: Iodobenzene can undergo a Sandmeyer reaction, where it is treated with a copper(I) salt and a source of nitrogen. This leads to the replacement of the iodine atom with a new functional group, such as an 【amine|https://www.ambeed.com/amines.html】, 【azide|https://www.ambeed.com/azides.html】, or 【cyanide|https://www.ambeed.com/nitriles.html】.
Grignard Reactions: Trifluoromethoxybenzene can react with Grignard reagents to form new carbon-carbon bonds. This is often used to introduce alkyl or aryl groups onto the benzene ring.
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