Home Chemistry Heterocyclic Building Blocks Benzofurans Benzofuran-3-Yl(Phenyl)Methanone
Acylation: The ketone group can be acylated to introduce other functional groups using reagents like acid chlorides or anhydrides in the presence of a Lewis acid catalyst.
Friedel-Crafts Acylation: This compound can undergo Friedel-Crafts acylation reactions with Lewis acids like aluminum chloride (AlCl3) to introduce an acyl group onto the benzofuran or phenyl ring.
Grignard Reaction: It can react with Grignard reagents (alkyl or aryl magnesium halides) to form alcohols or ketones, depending on the choice of the Grignard reagent.
Nucleophilic Addition: The carbonyl group in the ketone can undergo nucleophilic addition reactions with nucleophiles such as amines or hydrazines, leading to imine or hydrazone derivatives.
Ring Opening Reactions: The benzofuran ring can undergo various ring-opening reactions under specific conditions, leading to different products depending on the reagents and reaction conditions used.
Condensation Reactions: It can participate in condensation reactions with other compounds, forming new carbon-carbon or carbon-nitrogen bonds.
Heterocycle Synthesis: The benzofuran moiety can participate in various heterocycle synthesis reactions, such as Friedel-Crafts reactions, to form more complex heterocyclic compounds.
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone
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(5-Amino-2-butylbenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone oxalate
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(2-Butylbenzofuran-3-yl)(4-methoxyphenyl)methanone
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone
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