Home Chemistry Organic Building Blocks Bromides 2-Bromo-3-Fluoroaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—NH2).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Coupling Reactions: Aniline can participate in coupling reactions, such as Ullmann coupling, Buchwald-Hartwig coupling, and others, to form C-N bonds with various partner molecules.
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2-Bromo-3-fluoro-5-(trifluoromethyl)aniline
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3,6-Dibromo-4,5-difluorobenzene-1,2-diamine
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