Home Chemistry Organometallic Reagents Organoborons 2-(4-(Benzyloxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
Suzuki-Miyaura Coupling: The boron atom in the compound can participate in Suzuki-Miyaura coupling reactions with aryl halides or pseudohalides (e.g., aryl bromides or aryl triflates) in the presence of a palladium catalyst and a base. This reaction allows for the formation of new carbon-carbon bonds.
Hydroboration-Oxidation: The boron atom can also undergo hydroboration reactions with alkenes or alkynes, followed by oxidation with hydrogen peroxide or another suitable oxidizing agent to yield the corresponding alcohol.
Transmetallation: The boron atom can participate in transmetallation reactions with other organometallic reagents, such as organolithium or organomagnesium compounds, to form new boron-containing compounds.
Electrophilic Aromatic Substitution: The aromatic ring containing the benzyloxy group can undergo electrophilic aromatic substitution reactions, where it can react with electrophiles such as acyl chlorides, nitration reagents, or Friedel-Crafts reagents.
Deboronation: The boron atom can be removed from the molecule through deprotection reactions, typically using acid or base treatment, to regenerate the corresponding aryl compound.
Cross-Coupling Reactions: The boron atom can also participate in various cross-coupling reactions with other functional groups, such as halides, to form biaryl compounds.
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2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
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2-(4-(Benzyloxy)-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-(Benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-(Benzyloxy)-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-(Benzyloxy)-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-(Benzyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-((4-Chlorobenzyl)oxy)-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-((3-Chlorobenzyl)oxy)-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-((2-Chlorobenzyl)oxy)-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4-(Benzyloxy)-3-chloro-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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