Home Chemistry Heterocyclic Building Blocks Pyrrolidines 1-Phenylpyrrolidin-2-One
Acylation: It can undergo acylation reactions, where the carbonyl group can be reacted with acylating agents to form amides or esters. For example, reaction with an acid chloride or anhydride can lead to the formation of amides.
Bromination or Chlorination: The phenyl ring can be halogenated using bromine or chlorine in the presence of a suitable catalyst.
Grignard Reactions: 1-Phenylpyrrolidin-2-one can react with Grignard reagents to form various substituted derivatives.
Esterification: It can undergo esterification reactions with appropriate alcohol and acid catalysts to form ester derivatives.
Reductive Amination: It can be used as a substrate in reductive amination reactions to introduce amino groups.
Alkylation: The pyrrolidinone nitrogen can be alkylated to form various alkyl derivatives.
Cyclization: Depending on the reaction conditions, 1-phenylpyrrolidin-2-one can undergo cyclization reactions to form various cyclic compounds.
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5-Oxo-1-phenylpyrrolidine-3-carboxylic acid
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1-(2,6-Dimethylphenyl)-5-oxopyrrolidine-3-carboxylic acid
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3-Methoxy-4-(2-oxopyrrolidin-1-yl)benzoic acid
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4-Chloro-2-(2-oxopyrrolidin-1-yl)benzoic acid
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1-(2-Fluoro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid
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1-(4-Butylphenyl)-5-oxopyrrolidine-3-carboxylic acid
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