Home Chemistry Organic Building Blocks Bromides 2-Bromo-4-Fluorobenzoic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—COOH,—F).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Decarboxylation: Under certain conditions, benzoic acid can undergo decarboxylation, where it loses a carbon dioxide molecule from its carboxylic acid group. This reaction usually requires high temperatures and is often observed in the presence of strong acids or bases.
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Halogen related+−
Formula Weight+−
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :