Home Chemistry Heterocyclic Building Blocks Piperidines Benzyl 4-Oxopiperidine-1-Carboxylate
Hydrolysis: Benzyl 4-oxopiperidine-1-carboxylate can undergo hydrolysis in acidic or basic conditions, breaking the ester bond to form benzyl 4-oxopiperidine-1-carboxylic acid and benzyl alcohol or benzylamine, depending on the reaction conditions.
Esterification: The carboxylic acid group in benzyl 4-oxopiperidine-1-carboxylate can be esterified by reacting it with various alcohols in the presence of acid catalysts to form different esters.
Reductive Amination: The ketone group in the piperidone ring can undergo reductive amination with suitable amine reagents to form secondary or tertiary amines.
Nucleophilic Substitution: The benzyl group attached to the nitrogen in the piperidone ring can be substituted by various nucleophiles, leading to the formation of different products.
Reduction: The ketone group in the piperidone ring can be reduced to form the corresponding alcohol using reducing agents like sodium borohydride or lithium aluminum hydride.
Acylation: The amine group in the piperidone ring can undergo acylation reactions with acyl chlorides or anhydrides to introduce different acyl groups.
Alkylation: The amine group can also undergo alkylation reactions with alkyl halides to introduce various alkyl groups.
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Benzyl 3-amino-4-oxopiperidine-1-carboxylate hydrochloride
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Benzyl 2-methyl-4-oxopiperidine-1-carboxylate
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(R)-Benzyl 2-methyl-4-oxopiperidine-1-carboxylate
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Benzyl 2-ethyl-4-oxopiperidine-1-carboxylate
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1-Benzyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate
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Benzyl 3-methyl-4-oxopiperidine-1-carboxylate
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Benzyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
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Benzyl 3-fluoro-4-oxopiperidine-1-carboxylate
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Benzyl 3-bromo-4-oxopiperidine-1-carboxylate
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