RasGAP (Ras GTPase-activating proteins) are proteins that regulate the activity of Ras family GTPases by promoting the conversion of Ras from a GTP-bound active state to a GDP-bound inactive state. This family includes several members, such as NF1 and p120GAP, which function at different locations within the cell, involving processes like cell proliferation, differentiation, and apoptosis. RasGAPs are specifically expressed in different tissues, and their dysfunction or gene mutations are closely associated with the development of various cancers. For instance, mutations in the NF1 gene are linked to the pathogenesis of neurofibromatosis.