Chemistry Heterocyclic Building Blocks Triazoles 1-Phenyl-1H-1,2,4-Triazole

1-Phenyl-1H-1,2,4-Triazole

Substitution Reactions: 1-Phenyl-1H-1,2,4-triazole can undergo nucleophilic substitution reactions, where one or more atoms or groups on the molecule are replaced by other atoms or groups. For example, the phenyl group can be substituted with other groups like alkyl, acyl, or halogens. Nitration: You can nitrate 1-phenyl-1H-1,2,4-triazole to introduce nitro groups. Nitration is typically carried out by reacting the compound with a nitrating agent like concentrated nitric acid. Reduction: The triazole ring or other functional groups can be reduced using reducing agents like lithium aluminum hydride (LiAlH4) to produce corresponding reduced compounds. Oxidation: Depending on the reaction conditions, you can oxidize 1-phenyl-1H-1,2,4-triazole to introduce oxygen-containing functional groups. Halogenation: You can introduce halogen atoms (e.g., Cl, Br, F) into the molecule by reacting with appropriate halogenating agents. Formation of Derivatives: 1-Phenyl-1H-1,2,4-triazole can be used as a starting material to synthesize various derivatives by reacting it with different reagents and functional groups. Metalation: The compound can undergo metalation reactions where a metal atom or ion is introduced into the molecule. For example, you can react it with an organometallic reagent to form metal-1,2,4-triazole complexes. Cyclization Reactions: Depending on the reaction conditions, 1-phenyl-1H-1,2,4-triazole may undergo intramolecular cyclization reactions to form other cyclic compounds.

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(5As,10Br)-2-Phenyl-2,5A,6,10B-Tetrahydro-4H-Indeno[2,1-B][1,2,4]Triazolo[4,3-D][1,4]Oxazin-11-Ium 1-(Phenylsulfonyl)-1H-1,2,4-Triazole 1-Benzyl-1H-1,2,3-Triazole 1-Benzyl-1H-1,2,4-Triazole 1-Methyl-1H-1,2,3-Triazole 1-Methyl-1H-1,2,4-Triazole 1-Methyl-1H-Benzo[D][1,2,3]Triazole 1-Phenethyl-1H-1,2,4-Triazole 1-Phenyl-1H-1,2,3-Triazole 1-Phenyl-1H-1,2,4-Triazole 1H-1,2,4-Triazol-3-Amine 1H-1,2,4-Triazol-5-Amine 1H-Benzo[D][1,2,3]Triazol-1-Ol 2-Bromo-[1,2,4]Triazolo[1,5-A]Pyridine 2-Phenyl-2,5,6,7-Tetrahydropyrrolo[2,1-C][1,2,4]Triazol-4-Ium 2-Phenyl-2H-1,2,3-Triazole 2-Phenyl-2H-Benzo[D][1,2,3]Triazole 2H-1,2,3-Triazole 4-(4-Cyclopropylnaphthalen-1-Yl)-4H-1,2,4-Triazole 4-Phenyl-4H-1,2,4-Triazole 4-Phenyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepine 4H-1,2,4-Triazole 5-Bromo-1H-1,2,4-Triazole 5-Bromo-1H-Benzo[D][1,2,3]Triazole 5-Fluoro-1H-Benzo[D][1,2,3]Triazole 6-Bromo-[1,2,4]Triazolo[1,5-A]Pyridine 6-Bromo-[1,2,4]Triazolo[4,3-A]Pyridine 8-Bromo-[1,2,4]Triazolo[1,5-A]Pyridine [1,2,4]Triazolo[1,5-A]Pyrazine [1,2,4]Triazolo[1,5-A]Pyridin-2-Amine [1,2,4]Triazolo[4,3-A]Pyridin-3-Ylmethanamine Ethyl 1H-1,2,4-Triazole-3-Carboxylate

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