Home Chemistry Organic Building Blocks Bromides 1-Bromo-2,3-Dichlorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—Cl).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
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1-Bromo-2,3-dichloro-4-(2-methylpropoxy)benzene
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