Actin is a major component of the cytoskeleton, with family members including α-actin, β-actin, and γ-actin, among others. These proteins have a highly conserved globular structure and are widely distributed just beneath the plasma membrane and throughout the cell. Actin is involved in forming cellular structures, cell movement, division, and signaling pathways. Expression of the gene varies significantly across different cells and tissues, with mutations potentially leading to muscle diseases, cardiac issues, and cellular dysfunctions.