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Chemical Structure| 40106-98-7 Chemical Structure| 40106-98-7

Structure of 40106-98-7

Chemical Structure| 40106-98-7

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Product Details of [ 40106-98-7 ]

CAS No. :40106-98-7
Formula : C9H5ClN2O2
M.W : 208.60
SMILES Code : O=[N+](C1=C2C(Cl)=CC=NC2=CC=C1)[O-]
MDL No. :MFCD09261099
InChI Key :DWKLLQSQXXCSEW-UHFFFAOYSA-N
Pubchem ID :12582845

Safety of [ 40106-98-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 40106-98-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 40106-98-7 ]

[ 40106-98-7 ] Synthesis Path-Downstream   1~20

  • 1
  • [ 611-35-8 ]
  • [ 40106-98-7 ]
  • [ 23833-99-0 ]
YieldReaction ConditionsOperation in experiment
16%; 59% With sulfuric acid; nitric acid; at -15 - 20℃; for 3.0h; a. 4-Chloro-8-nitroquinoline (6a) and 4-chloro-5-nitroquinoline (6d). 4-Chloroquinoline (10.0 g, 61.3 mmol) was added in small portions to sulfuric acid (45 mL) taking care to maintain the temperature at or below [15 C.] Then the solution was cooled and maintained at-5 C during the addition of fuming nitric acid (9 mL). The mixture was allowed to warm to room temperature and stirred for an additional 3 h. The reaction mix was poured on ice and basified (pH 9) with NH40H. The resulting precipitate was filtered, washed well with water, dried, and recrystallized from methanol to provide 7.5 g (59%) [OF 6A] as golden-brown needles; mp [128-129 C] (lit. 32 mp [129-130 C) ; IH NMR (CDC13)] [6] 7.67 (d, 1H, [J=4.] 5), 7.75 (dd, 1H, [J=8.] 6,. [J=7.] 6), 8.10 (dd, 1H, [J=7.] 6, [J=1.] 3), 8. 48 (dd, 1H, [J=8.] 6, J=1. 3), 8.94 (d, 1H, J=4. 5); [13C] NMR (CDC13) [6] 123.0, 124.4, 126.5, 127.5, 128.3, 140.6, 143.2, 148.7, 152.1. The mother liquor was evaporated and chromatographed in 19: 1 hexanes-ethyl acetate, to provide 2.05 g (16%) of the 5-nitro isomer 6d as a very light yellow solid; mp [144-146 C] (lit. 31 mp [150 C) ; IH] NMR (CDCl3) [6] 7.65 (d, 1H, J=4. 7), 7. 82 [(M,] 2H), 8.35 (dd, [1H,] [J=2.] 5, J=7. 3), 8.90 (d, 1H, J=4. 7); [13C] NMR [(CDC13)] 8 118.2, 123.4, 125.1, 128.8, 134.2, 135.6, 139.1, 149.7, 151.2.
  • 4
  • [ 40106-98-7 ]
  • [ 142-25-6 ]
  • N,N,N'-Trimethyl-N'-(5-nitro-quinolin-4-yl)-ethane-1,2-diamine [ No CAS ]
  • 6
  • [ 40106-98-7 ]
  • [ 109-55-7 ]
  • [ 80552-29-0 ]
  • 7
  • [ 40106-98-7 ]
  • [ 3529-10-0 ]
  • N,N-Dimethyl-N'-(5-nitro-quinolin-4-yl)-butane-1,4-diamine [ No CAS ]
  • 8
  • [ 40107-10-6 ]
  • [ 18436-76-5 ]
  • [ 40106-98-7 ]
  • 9
  • [ 2038-03-1 ]
  • [ 40106-98-7 ]
  • (2-Morpholin-4-yl-ethyl)-(5-nitro-quinolin-4-yl)-amine [ No CAS ]
  • 10
  • [ 40106-98-7 ]
  • [ 616-30-8 ]
  • 3-(5-Nitro-quinolin-4-ylamino)-propane-1,2-diol [ No CAS ]
  • 11
  • [ 40106-98-7 ]
  • [ 188758-93-2 ]
  • N-(2-Dimethylamino-ethyl)-4-(5-nitro-quinolin-4-ylamino)-benzamide; hydrochloride [ No CAS ]
  • 12
  • [ 40106-98-7 ]
  • [ 109-73-9 ]
  • Butyl-(5-nitro-quinolin-4-yl)-amine [ No CAS ]
  • 13
  • [ 40106-98-7 ]
  • [ 156-87-6 ]
  • 3-(5-Nitro-quinolin-4-ylamino)-propan-1-ol [ No CAS ]
  • 15
  • [ 611-35-8 ]
  • [ 7664-93-9 ]
  • [ 7697-37-2 ]
  • [ 40106-98-7 ]
  • [ 23833-99-0 ]
  • 16
  • [ 40106-98-7 ]
  • 4-amino-8,9-dimethoxy-5-[2-(N,N-dimethylamino)ethyl]-5H-dibenzo[c,h][1,6]naphthyridin-6-one [ No CAS ]
  • 17
  • [ 40106-98-7 ]
  • [ 658710-20-4 ]
  • 18
  • [ 40106-98-7 ]
  • [ 658710-33-9 ]
  • 19
  • [ 529-37-3 ]
  • [ 40106-98-7 ]
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 40106-98-7 ]

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Related Parent Nucleus of
[ 40106-98-7 ]

Quinolines

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