Home Chemistry Heterocyclic Building Blocks Indoles 1-Methyl-1H-Indole-2-Carboxylic Acid
Esterification: The carboxylic acid group can undergo esterification reactions with alcohols to form ester compounds. This typically involves the use of a condensation agent or a catalyst.
Amide Formation: The carboxylic acid group can react with amines to form amide compounds. This can be achieved by using coupling agents or activating reagents.
Decarboxylation: Under certain conditions, the carboxylic acid group may undergo decarboxylation, leading to the removal of the carboxyl group and the formation of an indole derivative.
Nucleophilic Substitution: The indole nucleus, particularly the positions adjacent to the carboxylic acid group, can undergo nucleophilic substitution reactions with appropriate nucleophiles.
Oxidation: The methyl group on the indole ring is a potential site for oxidation reactions, converting the methyl group to a carboxyl group or other oxidized forms.
Reduction: The carbonyl group in the carboxylic acid moiety can undergo reduction reactions to yield alcohols or other reduced products.
Nucleophilic Addition: The double bond in the indole ring can undergo nucleophilic addition reactions under appropriate conditions.
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6-Bromo-1-methyl-1H-indole-2-carboxylic acid
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6-Fluoro-1-methyl-1H-indole-2-carboxylic acid
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6-Methoxy-1-methyl-1H-indole-2-carboxylic acid
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5-Chloro-1-methyl-1H-indole-2-carboxylic acid
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3-Bromo-1-methyl-1H-indole-2-carboxylic acid
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4-Fluoro-1-methyl-1H-indole-2-carboxylic acid
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5,6-Dihydroxy-1-methyl-1H-indole-2-carboxylic acid
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