Home Chemistry Organic Building Blocks Chlorides 2-Chloro-1,4-Difluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—F).
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
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3-Chloro-2,4,5-trifluorobenzoyl chloride
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Ethyl 3-(3-chloro-2,4,5-trifluorophenyl)-3-oxopropanoate
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