Home Chemistry Heterocyclic Building Blocks Piperidines Piperidine-3-Carboxamide
Substitution Reactions: The nitrogen atom in the piperidine ring can undergo nucleophilic substitution reactions with various electrophiles, leading to the formation of substituted derivatives.
Acylation: The nitrogen atom in the piperidine ring can undergo acylation reactions to form N-acyl derivatives.
Reduction: The carbonyl group can be reduced to the corresponding amine using reducing agents such as lithium aluminum hydride or sodium borohydride.
Amidation: The carboxylic acid group can react with amines to form amides.
Hydrolysis: The amide group can undergo hydrolysis under acidic or basic conditions to yield the corresponding carboxylic acid and amine.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Protonation: The amide group can be protonated under acidic conditions to form the corresponding ammonium salt.
Dehydration: Under appropriate conditions, dehydration reactions can occur to eliminate water and form unsaturated compounds.
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(R)-tert-Butyl 3-carbamoylpiperidine-1-carboxylate
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