Home Chemistry Organic Building Blocks Bromides 3-Bromo-4-Methylbenzoic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—CH3,—COOH).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Sulfonation: Toluene can be sulfonated, leading to the introduction of a sulfonic acid group (-SO3H) onto the benzene ring. This is often carried out using concentrated sulfuric acid.
Neutralization Reaction with Bases: Benzoic acid can react with bases to form water-soluble salts called benzoates. The reaction is a typical acid-base neutralization reaction, where the hydrogen ion from the carboxylic acid group is replaced by a metal cation or another positively charged organic group.
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