Platelets are anucleate cell fragments derived from megakaryocytes in the bone marrow, primarily responsible for blood coagulation and wound healing. They circulate in the bloodstream, contributing to hemostasis by interacting with the vessel wall and releasing clotting factors. Platelets possess a variety of receptors on their surface to respond to injury signals, activating and aggregating at the site of damage. Specific gene expression plays a crucial role in the regulation of platelet formation, function, and lifespan, while genetic mutations can lead to coagulation disorders, such as thrombocytopenia or functional abnormalities.