Home Chemistry Heterocyclic Building Blocks Indoles (3As,7As)-Octahydro-1H-Indole
Ring Opening Reactions: The saturated seven-membered ring can undergo ring-opening reactions under specific conditions. For example, treatment with strong acids or bases can lead to ring cleavage and the formation of different products.
Acylation: You can react (3aS,7aS)-octahydro-1H-indole with acylating agents like acyl chlorides or anhydrides to introduce acyl groups to the molecule. This can lead to the formation of amides.
Alkylation: You can perform alkylation reactions using alkyl halides or other alkylating agents to introduce alkyl groups onto the indole nitrogen or other available positions.
Reduction: (3aS,7aS)-Octahydro-1H-indole can undergo reduction reactions with reducing agents like hydrogen and a metal catalyst to produce saturated or partially saturated derivatives.
Oxidation: Oxidation reactions can convert (3aS,7aS)-octahydro-1H-indole into different products, such as indole derivatives or compounds with oxidized functional groups.
Substitution Reactions: Depending on the reaction conditions and reagents, various substitution reactions, including nucleophilic aromatic substitution, can occur at the indole ring.
Cyclization: You can explore intramolecular cyclization reactions to form fused ring systems or other cyclic compounds.
Functional Group Transformations: (3aS,7aS)-Octahydro-1H-indole can be subjected to various functional group transformations, such as halogenation, hydroxylation, or other reactions to modify its chemical structure.
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(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic Acid
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(2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
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(2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride
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