Home Chemistry Organic Building Blocks Iodides 2-Bromo-4-Chloro-1-Iodobenzene
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —I,—Br,—Cl).
Electrophilic Aromatic Substitution (EAS): Iodobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The presence of the iodine atom makes the ring more reactive toward electrophiles due to its electron-donating inductive effect. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Electrophilic Aromatic Substitution (EAS): Bromobenzene can react with electrophiles in substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts acylation/alkylation.
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
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1-Bromo-5-chloro-2-iodo-3-methoxybenzene
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