Home Chemistry Organic Building Blocks Amides N-Phenylpivalamide
These compounds have the same murcko framework: benzene,and at least 1 kind of functional groups( —NHC(O)C(CH3)3).
An amide group (-CONH-): 【Amides|https://www.ambeed.com/amides.html】 are relatively stable and are not very reactive under normal conditions. They can undergo reactions such as hydrolysis (in the presence of acids or bases) to yield 【carboxylic acids|https://www.ambeed.com/carboxylic-acids.html】 and 【amines|https://www.ambeed.com/amines.html】, or they can participate in acylation reactions.
A phenyl group (C6H5-): The phenyl group is an aromatic ring, and it can participate in electrophilic aromatic substitution reactions when activated by electron-donating or withdrawing groups.
A pivaloyl group (tert-butyl group, -t-Bu): The tert-butyl group is a bulky alkyl group, and it tends to hinder reactions at the site of attachment due to steric hindrance. However, it can also act as a protecting group in synthetic chemistry.
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N-(3-(Trifluoromethyl)phenyl)pivalamide
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