Home Chemistry Heterocyclic Building Blocks Pyridines 5-Iodopyridin-2-Amine
Substitution Reactions: The iodine atom can undergo substitution reactions with various nucleophiles such as amines, alcohols, thiols, etc., leading to the formation of substituted products.
Metalation Reactions: The amino group can coordinate with metal ions, leading to metalation reactions. This can further facilitate various synthetic transformations.
Cross-Coupling Reactions: The iodine atom can participate in cross-coupling reactions, such as Suzuki, Stille, or Heck reactions, where it couples with another organic halide or pseudohalide in the presence of suitable catalysts.
Reductive Reactions: The iodine atom can undergo reductive transformations under appropriate conditions, leading to the formation of products with reduced iodine content.
Nucleophilic Aromatic Substitution (SNAr): The amino group can act as a nucleophile in SNAr reactions, displacing the iodine atom and leading to the formation of various substituted products.
Functional Group Transformations: The amino group can undergo various functional group transformations such as acylation, alkylation, and formylation, leading to the introduction of new functional groups at the amino position.
Cyclization Reactions: Depending on the structure and conditions, cyclization reactions involving the amino group and adjacent functional groups can occur, leading to the formation of cyclic compounds.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :