Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1,3-Difluoro-2-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—NO2).
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Halogenation: Nitrobenzene can undergo halogenation reactions, where halogen atoms (such as chlorine or bromine) are substituted onto the benzene ring. This is usually achieved using halogenating agents in the presence of a catalyst.
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