32326-25-3|5-Methoxyisoxazol-3-amine| Ambeed

Size	Price	VIP Price	US Stock	Global Stock	In Stock
{[ item.pr_size ]}		Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

{[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

Quality Control of [ 32326-25-3 ] Purity: 97% SDS Specification

COA

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

NMR

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

CNMR

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

HPLC

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

LC-MS

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

1-2 Day Shipping
High Quality
Technical Support

Product Details of [ 32326-25-3 ]

CAS No. :	32326-25-3
Formula :	C₄H₆N₂O₂
M.W :	114.10
SMILES Code :	COC1=CC(=NO1)N
MDL No. :	MFCD09701967
InChI Key :	PVDLBNRYTGXVPC-UHFFFAOYSA-N
Pubchem ID :	11007859

Safety of [ 32326-25-3 ]

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302-H315-H319-H335
Precautionary Statements:	P261-P305+P351+P338

Application In Synthesis of [ 32326-25-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 32326-25-3 ]

[ 32326-25-3 ] Synthesis Path-Downstream 1~14

1
[ 333-20-0 ]
[ 541-41-3 ]
[ 32326-25-3 ]
[ 150215-07-9 ]

References: [1]Tetrahedron Letters,1993,vol. 34,p. 6423 - 6426.
[2]Bulletin of the Chemical Society of Japan,1994,vol. 67,p. 1701 - 1707.

2
[ 333-20-0 ]
[ 501-53-1 ]
[ 32326-25-3 ]
[ 150215-09-1 ]

References: [1]Tetrahedron Letters,1993,vol. 34,p. 6423 - 6426.
[2]Bulletin of the Chemical Society of Japan,1994,vol. 67,p. 1701 - 1707.

3
[ 333-20-0 ]
[ 79-22-1 ]
[ 32326-25-3 ]
[ 149196-71-4 ]

References: [1]Tetrahedron Letters,1993,vol. 34,p. 6423 - 6426.
[2]Bulletin of the Chemical Society of Japan,1994,vol. 67,p. 1701 - 1707.

4
[ 333-20-0 ]
[ 1885-14-9 ]
[ 32326-25-3 ]
[ 150215-08-0 ]

References: [1]Tetrahedron Letters,1993,vol. 34,p. 6423 - 6426.
[2]Bulletin of the Chemical Society of Japan,1994,vol. 67,p. 1701 - 1707.

5
[ 15732-02-2 ]
[ 32326-25-3 ]

Yield	Reaction Conditions	Operation in experiment
70.6%	With sodium hydroxide; hydroxylamine hydrochloride; In methanol; water;	(B) To a solution of hydroxylamine hydrochloride (1.55 g, 22.3 mmol) in water (3.41 ml) was added 8N aqueous sodium hydroxide solution (3.35 ml; 26.8 mmol) under stirring at room temperature. The temperature was elvated to 45 C. and a solution of 3,3-dimethoxyacrylonitrile (2.27 g; 20.1 mmol) in methanol (5.50 ml) was added dropwise for 30 minutes and then the mixture was stirred at the same temperature for 1 hour. After disappear of 3,3-dimethoxyacrylonitrile was apparent, 8N sodium hydroxide (1.25 ml; 10.1 mmol) was added to the mixture at the same temperature and the temperature was elevated to 60 C. The mixture was stirred for 6 hours. After the reaction was completed, the reaction mixture was directly concentrated (60 C./19 mmHg: until an inorganic compound was begun to precipitate). The obtained concentrate was extracted with ethyl acetate (5 ml*3) and the extract was dried over sodium sulfate and concentrated and the residue was dried under reduced pressure to give 3-amino-5-methoxyisoxazole (1.63 g; yield 70.6%) as white crystals. m.p. 82-83 C. (hexane-ethyl acetate) NMR delta (CDCl3): 3.93(5H,bs,CH3 +NH2), 4.81(1H,s,H-4) NMR delta (CDCl3 +D2 O): 3.93 (3H,s,CH3), 4.83(1H,s,H-4) IR (CHL3)cm-1: 3840, 1628, 1487. Anal. Calcd. for C4 H6 N2 O2: C,42.11;H,5.30; N 24.55(%). Found: C,41.74; H, 5.06; N, 24.35(%).

References: [1]Bulletin of the Chemical Society of Japan,1994,vol. 67,p. 1701 - 1707.
[2]Patent: US5585494,1996,A .

6
[2-methyl-1-(pyrazolidine-1-carbonyl)-butyl]-carbamic acid <i>tert</i>-butyl ester [ No CAS ]
[ 75-44-5 ]
[ 32326-25-3 ]
{1-[2-(5-methoxy-isoxazol-3-ylcarbamoyl)-pyrazolidine-1-carbonyl]-2-methyl-butyl}-carbamic acid <i>tert</i>-butyl ester [ No CAS ]

References: [1]Chemical and Pharmaceutical Bulletin,2005,vol. 53,p. 1048 - 1050.

7
[ 541-41-3 ]
[ 32326-25-3 ]
[ 150215-07-9 ]

Yield	Reaction Conditions	Operation in experiment
78.9%	In acetonitrile;	Example 2 A suspension of ethyl chloroformate (124 mul; 1.29 mmol) and potassium thiocyanate (136 mg; 1.40 mmol) in acetonitrile (1.08 ml) was treated with <strong>[32326-25-3]<strong>[32326-25-3]3-amino-5-methoxyisoxazol</strong>e</strong> (123 mg; 1.08 mmol) in the same manner as in Example 1 except that ethyl chloroformate was substituted for methyl chloroformate to give methyl 2-(5-ethoxycarbonylamino-1,2,4-thiadiazol-3yl)acetate (209 mg; yield 78.9%). m.p. 110-112 C. (MeOH) NMR delta (CDCl3): 1.38(3H.t.CH3) 3.73(3H.s.COOCH3) 3.97(2H.s.CH2 COOCH3) 4.39(2H.q. CH2) 10.45(1H.bs.NH) IR(CHCl3)cm-1: 3406, 1732, 1564. Anal. Calcd. for C8 H11 N3 O4 S: C,39.18; H, 4.52; N, 17.13(%). Found: C,39.16; H,4.40; N,17.18(%).