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Chemical Structure| 194152-05-1 Chemical Structure| 194152-05-1
Chemical Structure| 194152-05-1

4-Hydroxytetrahydro-2H-thiopyran 1,1-dioxide

CAS No.: 194152-05-1

4.5 *For Research Use Only !

Cat. No.: A102675 Purity: 98%

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Product Details of [ 194152-05-1 ]

CAS No. :194152-05-1
Formula : C5H10O3S
M.W : 150.20
SMILES Code : OC1CCS(=O)(=O)CC1
MDL No. :MFCD12152579
InChI Key :JABSMKPYEZTJTE-UHFFFAOYSA-N
Pubchem ID :45791255

Safety of [ 194152-05-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Calculated chemistry of [ 194152-05-1 ] Show Less

Physicochemical Properties

Num. heavy atoms 9
Num. arom. heavy atoms 0
Fraction Csp3 1.0
Num. rotatable bonds 0
Num. H-bond acceptors 3.0
Num. H-bond donors 1.0
Molar Refractivity 34.16
TPSA ?

Topological Polar Surface Area: Calculated from
Ertl P. et al. 2000 J. Med. Chem.

62.75 Ų

Lipophilicity

Log Po/w (iLOGP)?

iLOGP: in-house physics-based method implemented from
Daina A et al. 2014 J. Chem. Inf. Model.

0.7
Log Po/w (XLOGP3)?

XLOGP3: Atomistic and knowledge-based method calculated by
XLOGP program, version 3.2.2, courtesy of CCBG, Shanghai Institute of Organic Chemistry

-0.53
Log Po/w (WLOGP)?

WLOGP: Atomistic method implemented from
Wildman SA and Crippen GM. 1999 J. Chem. Inf. Model.

0.64
Log Po/w (MLOGP)?

MLOGP: Topological method implemented from
Moriguchi I. et al. 1992 Chem. Pharm. Bull.
Moriguchi I. et al. 1994 Chem. Pharm. Bull.
Lipinski PA. et al. 2001 Adv. Drug. Deliv. Rev.

-0.48
Log Po/w (SILICOS-IT)?

SILICOS-IT: Hybrid fragmental/topological method calculated by
FILTER-IT program, version 1.0.2, courtesy of SILICOS-IT, http://www.silicos-it.com

0.27
Consensus Log Po/w?

Consensus Log Po/w: Average of all five predictions

0.12

Water Solubility

Log S (ESOL):?

ESOL: Topological method implemented from
Delaney JS. 2004 J. Chem. Inf. Model.

-0.44
Solubility 54.9 mg/ml ; 0.365 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Very soluble
Log S (Ali)?

Ali: Topological method implemented from
Ali J. et al. 2012 J. Chem. Inf. Model.

-0.32
Solubility 72.1 mg/ml ; 0.48 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Very soluble
Log S (SILICOS-IT)?

SILICOS-IT: Fragmental method calculated by
FILTER-IT program, version 1.0.2, courtesy of SILICOS-IT, http://www.silicos-it.com

-0.37
Solubility 64.2 mg/ml ; 0.428 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Soluble

Pharmacokinetics

GI absorption?

Gatrointestinal absorption: according to the white of the BOILED-Egg

High
BBB permeant?

BBB permeation: according to the yolk of the BOILED-Egg

No
P-gp substrate?

P-glycoprotein substrate: SVM model built on 1033 molecules (training set)
and tested on 415 molecules (test set)
10-fold CV: ACC=0.72 / AUC=0.77
External: ACC=0.88 / AUC=0.94

No
CYP1A2 inhibitor?

Cytochrome P450 1A2 inhibitor: SVM model built on 9145 molecules (training set)
and tested on 3000 molecules (test set)
10-fold CV: ACC=0.83 / AUC=0.90
External: ACC=0.84 / AUC=0.91

No
CYP2C19 inhibitor?

Cytochrome P450 2C19 inhibitor: SVM model built on 9272 molecules (training set)
and tested on 3000 molecules (test set)
10-fold CV: ACC=0.80 / AUC=0.86
External: ACC=0.80 / AUC=0.87

No
CYP2C9 inhibitor?

Cytochrome P450 2C9 inhibitor: SVM model built on 5940 molecules (training set)
and tested on 2075 molecules (test set)
10-fold CV: ACC=0.78 / AUC=0.85
External: ACC=0.71 / AUC=0.81

No
CYP2D6 inhibitor?

Cytochrome P450 2D6 inhibitor: SVM model built on 3664 molecules (training set)
and tested on 1068 molecules (test set)
10-fold CV: ACC=0.79 / AUC=0.85
External: ACC=0.81 / AUC=0.87

No
CYP3A4 inhibitor?

Cytochrome P450 3A4 inhibitor: SVM model built on 7518 molecules (training set)
and tested on 2579 molecules (test set)
10-fold CV: ACC=0.77 / AUC=0.85
External: ACC=0.78 / AUC=0.86

No
Log Kp (skin permeation)?

Skin permeation: QSPR model implemented from
Potts RO and Guy RH. 1992 Pharm. Res.

-7.59 cm/s

Druglikeness

Lipinski?

Lipinski (Pfizer) filter: implemented from
Lipinski CA. et al. 2001 Adv. Drug Deliv. Rev.
MW ≤ 500
MLOGP ≤ 4.15
N or O ≤ 10
NH or OH ≤ 5

0.0
Ghose?

Ghose filter: implemented from
Ghose AK. et al. 1999 J. Comb. Chem.
160 ≤ MW ≤ 480
-0.4 ≤ WLOGP ≤ 5.6
40 ≤ MR ≤ 130
20 ≤ atoms ≤ 70

None
Veber?

Veber (GSK) filter: implemented from
Veber DF. et al. 2002 J. Med. Chem.
Rotatable bonds ≤ 10
TPSA ≤ 140

0.0
Egan?

Egan (Pharmacia) filter: implemented from
Egan WJ. et al. 2000 J. Med. Chem.
WLOGP ≤ 5.88
TPSA ≤ 131.6

0.0
Muegge?

Muegge (Bayer) filter: implemented from
Muegge I. et al. 2001 J. Med. Chem.
200 ≤ MW ≤ 600
-2 ≤ XLOGP ≤ 5
TPSA ≤ 150
Num. rings ≤ 7
Num. carbon > 4
Num. heteroatoms > 1
Num. rotatable bonds ≤ 15
H-bond acc. ≤ 10
H-bond don. ≤ 5

1.0
Bioavailability Score?

Abbott Bioavailability Score: Probability of F > 10% in rat
implemented from
Martin YC. 2005 J. Med. Chem.

0.55

Medicinal Chemistry

PAINS?

Pan Assay Interference Structures: implemented from
Baell JB. & Holloway GA. 2010 J. Med. Chem.

0.0 alert
Brenk?

Structural Alert: implemented from
Brenk R. et al. 2008 ChemMedChem

0.0 alert: heavy_metal
Leadlikeness?

Leadlikeness: implemented from
Teague SJ. 1999 Angew. Chem. Int. Ed.
250 ≤ MW ≤ 350
XLOGP ≤ 3.5
Num. rotatable bonds ≤ 7

No; 1 violation:MW<1.0
Synthetic accessibility?

Synthetic accessibility score: from 1 (very easy) to 10 (very difficult)
based on 1024 fragmental contributions (FP2) modulated by size and complexity penaties,
trained on 12'782'590 molecules and tested on 40 external molecules (r2 = 0.94)

2.63

Application In Synthesis of [ 194152-05-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 194152-05-1 ]

[ 194152-05-1 ] Synthesis Path-Downstream   1~29

  • 1
  • [ 194152-05-1 ]
  • [ 75-36-5 ]
  • [ 38690-86-7 ]
  • 2
  • [ 194152-05-1 ]
  • [ 77-78-1 ]
  • 4-methoxy-tetrahydro-thiopyran-1,1-dioxide [ No CAS ]
  • 3
  • [ 194152-05-1 ]
  • [ 38690-84-5 ]
  • 4
  • [ 194152-05-1 ]
  • 4-iodo-tetrahydro-thiopyran-1,1-dioxide [ No CAS ]
  • 5
  • [ 17396-35-9 ]
  • [ 194152-05-1 ]
  • 6
  • [ 7732-18-5 ]
  • [ 17396-35-9 ]
  • Raney nickel [ No CAS ]
  • [ 194152-05-1 ]
  • 8
  • [ 358-23-6 ]
  • [ 194152-05-1 ]
  • [ 473543-31-6 ]
  • 9
  • [ 194152-05-1 ]
  • [ 827038-81-3 ]
  • [ 827038-86-8 ]
  • 10
  • [ 1072-72-6 ]
  • [ 194152-05-1 ]
  • 11
  • [ 194152-05-1 ]
  • [ 473543-32-7 ]
  • 12
  • [ 194152-05-1 ]
  • dicyclohexyl-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-phosphane; compound with borane [ No CAS ]
  • 13
  • [ 29683-23-6 ]
  • [ 881025-65-6 ]
  • [ 194152-05-1 ]
  • 14
  • [ 1319737-92-2 ]
  • [ 194152-05-1 ]
  • [ 1319737-91-1 ]
YieldReaction ConditionsOperation in experiment
15% With di-tert-butyl-diazodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; at 20℃; Example 10: (R)-4-((7-(1 ,1 -dioxo-hexahydro-^a*6*-thiopyran-4-yloxy-3-methoxy- phenyl)-1 ,6-naphthyridine-5-yloxy)methyl)pyrrolidine-2-oneExample 53 Example 1078 mg (R)-4-[7-(4-Hydroxy-3-methoxy-phenyl)-[1 ,6]naphthyridine-5-yloxymethyl]-pyrrolidine- 2-one (Example 53), 38 mg (0.25 mmol) 1 , 1 -dioxo-hexahydro-1 *6*-thiopyran-4-ol and 1 12 mg triphenylphosphine was suspended in 5 mL tetrahydrofuran. 98 mg DBAD and 1 ml_ dichloromethane was added and the mixture was stirred overnight at ambient temperature. Further 50 mg triphenylphosphine and 40 mg DBAD was added and stirred for further 24 h. The mixture was concentrated, then dissolved in methanol and diluted with water and purified by chromatography (RP-HPLC-MS).Yield: 16 mg (15percent of theory)Analysis: HPLC-MS (method E): Rt: 1 .1 1 min, (M+H)+: 498
15% With di-tert-butyl-diazodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; at 20℃; 78 mg (R)-447-(4-Hydroxy-3-methoxy-phenyl)-[1,6]naphthyridine-5-yloxymethyl]-pyrrolidine-2-one (Example 53), 38 mg (0.25 mmol) 1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-ol and 112 mg triphenylphosphine was suspended in 5 mL tetrahydrofuran.98 mg DBAD and 1 mL dichloromethane was added and the mixture was stirred overnight at ambient temperature.Further 50 mg triphenylphosphine and 40 mg DBAD was added and stirred for further 24 h.The mixture was concentrated, then dissolved in methanol and diluted with water and purified by chromatography (RP-HPLC-MS).Yield: 16 mg (15percent of theory)Analysis: HPLC-MS (method E): Rt: 1.11 min, (M+H)+: 498
  • 15
  • [ 194152-05-1 ]
  • [ 124-63-0 ]
  • [ 1458653-10-5 ]
YieldReaction ConditionsOperation in experiment
95% With triethylamine; In dichloromethane; at 0 - 20℃; for 3.16667h; Step 1. l,l-dioxidotetrahydro-2H-thiopyran-4-yl methanesulfonate [0705] Triethylamine (7.80 mL, 55.9 mmol) was added to a solution of 4-hydroxytetrahydro-2H- thiopyran 1,1-dioxide (3.5 g, 23.3 mmol) in dichloromethane (35.0 mL). The reaction solution was cooled to 0 °C and methanesulfonyl chloride (3.25 ml, 41.9 mmol) was added. After 10 minutes, the reaction solution was warmed to room temperature and stirred for 3 h. The reaction was quenched via the addition of saturated aqueous ammonium chloride solution (15 mL). The organic layer was separated and washed with saturated aqueous sodium bicarbonate solution (15 mL) and brine (15 mL), dried over anhydrous sodium sulfate, filtered and concentrated in vacuo to afford an off-white solid. The solid residue was suspended in ethyl acetate (20 mL) and filtered. The filtered solid was then collected and dried in vacuo affording 1 , 1 -dioxidotetrahydro-2H-thiopyran-4-yl methanesulfonate (5.1 g, 95percent) as a white solid. 1H NMR (400 MHz, CDC13) delta ppm 2.38 - 2.56 (m, 4 H) 2.94 - 3.06 (m, 2 H) 3.10 (s, 3 H) 3.23 - 3.39 (m, 2 H) 5.03 (tt, J=4.74, 2.49 Hz, 1 H)
95% With triethylamine; In dichloromethane; at 0 - 20℃; for 3.16h; Triethylamine (7.80 mL, 55.9 mmol) was added to a solution of 4-hydroxytetrahydro- 2H-thiopyran 1,1-dioxide (3.5 g, 23.3 mmol) in dichloromethane (35.0 mL). The reaction solution was cooled to 0 °C and methanesulfonyl chloride (3.25 ml, 41.9 mmol) was added. After 10 minutes, the reaction solution was warmed to room temperature and stirred for 3 h. The reaction was quenched via the addition of saturated aqueous ammonium chloride solution (15 mL). The organic layer was separated and washed with saturated aqueous sodium bicarbonate solution (15 mL) and brine (15 mL), dried over anhydrous sodium sulfate, filtered and concentrated in vacuo to afford an off-white solid. The solid residue was suspended in ethyl acetate (20 mL) and filtered. The filtered solid was then collected and dried in vacuo affording 1,1-dioxidotetrahydro-2H-thiopyran-4-yl methanesulfonate (5.1 g, 95percent) as a white solid.1H NMR (400 MHz, CDCl3) delta ppm 2.38 - 2.56 (m, 4 H) 2.94 - 3.06 (m, 2 H) 3.10 (s, 3 H) 3.23 - 3.39 (m, 2 H) 5.03 (tt, J = 4.74, 2.49 Hz, 1 H)
75% With triethylamine; In dichloromethane; at 20℃; A 250-mL round-bottom flask was charged with <strong>[194152-05-1]4-hydroxy-thiane-1,1-dione</strong> (3.50 g, 23.3 mmol, 1.00 equiv), methanesulfonyl chloride (5.30 g, 46.5 mmol, 2.00 equiv), triethylamine (7.10 g, 70.2 mmol, 3.00 equiv), and DCM (40 mL). The resulting solution was stirred overnight at room temperature and then quenched with water (40 mL). The resulting mixture was extracted with DCM (3 x 30 mL) and the organic layers were combined, washed with brine (1 x 200 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was chromatographed on a silica gel column to provide 4.00 g (75percent yield) of 1,1 -dioxo-thian-4-yl methanesulfonate as a white solid.
75% With triethylamine; In dichloromethane; at 20℃; Example 175: 1,1,1,3,3,3-Hexafluoropropan-2-yl 1-(2-((1,1-dioxidotetrahydro-2H-thiopyran- 4-yl)oxy)-4-(trifluoromethyl)benzyl)-1,8-diazaspiro[4.5]decane-8-carboxylate Step 1: Synthesis of 1,1-dioxidotetrah dro-2H-thio ran methanesulfonate A flask was charged with <strong>[194152-05-1]4-hydroxytetrahydro-2H-thiopyran 1,1-dioxide</strong> (3.50 g, 23.3 mmol, 1.00 equiv), methanesulfonyl chloride (5.30 g, 46.5 mmol, 2.00 equiv), TEA (7.10 g, 70.2 mmol, 3.00 equiv), and DCM (40 mL). The resulting solution was stirred overnight at rt and quenched with H2O (40 mL). The resulting mixture was extracted with DCM (3 x 30 mL) and the organic layers were combined, washed with brine (200 mL), dried over anhydrous sodium sulfate, filtered, and concentrated. The residue was chromatographed on a silica gel column with EtOAc/petroleum ether (10/1) to provide 4.00 g (75percent yield) of 1,1-dioxidotetrahydro-2H- thiopyran-4-yl methanesulfonate as a white solid.

  • 16
  • [ 194152-05-1 ]
  • methyl (2S)-5-cyclobutoxy-6-[1-(1,1-dioxo-1λ6-thian-4-yl)-1H-pyrazol-4-yl]-2-methyl-1,2,3,4-tetrahydroquinoline-1-carboxylate [ No CAS ]
  • 17
  • [ 194152-05-1 ]
  • 4-(4-iodo-1H-pyrazol-1-yl)tetrahydro-2H-thiopyran-1,1-dioxide [ No CAS ]
  • 18
  • [ 194152-05-1 ]
  • 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)tetrahydro-2H-thiopyran-1,1-dioxide [ No CAS ]
  • 19
  • [ 194152-05-1 ]
  • cyclobutyl (3S)-4-acetyl-7-[1-(1,1-dioxo-1λ6-thian-4-yl)-1H-pyrazo1-4-yl]-3-methyl-1,2,3,4-tetrahydroquinoxaline-1-carboxylate [ No CAS ]
  • 20
  • [ 194152-05-1 ]
  • cyclopropylmethyl (3S)-4-acetyl-7-[1-(1,1-dioxo-1λ6-thian-4-yl)-1H-pyrazol-4-yl]-3-methyl-1,2,3,4-tetrahydroquinoxaline-1-carboxylate [ No CAS ]
  • cyclopropylmethyl (3S)-4-acetyl-7-{1-[(3S)-1,1-dioxo-1λ6-thian-3-yl]-1H-pyrazol-4-yl}-3-methyl-1,2,3,4-tetrahydroquinoxaline-1-carboxylate [ No CAS ]
  • 21
  • [ 1383474-84-7 ]
  • [ 194152-05-1 ]
  • ethyl 7-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)oxy)imidazo[1,2-a]pyridine-3-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
76% With tributylphosphine; 1,1'-azodicarbonyl-dipiperidine; In toluene; at 20 - 150℃; for 0.25h;Microwave irradiation; To a microwave vial containing ethyl 7-hydroxyimidazo[ 1 ,2-a]pyridine-3-carboxylate (50 mg, 0.24 mmol), <strong>[194152-05-1]4-hydroxytetrahydro-2H-thiopyran 1,1-dioxide</strong> (73 mg, 0.49 mmol), 1,1 ?-(azodicarbonyl)dipiperidine (184 mg, 0.73 mmol) were added toluene (3 mL) and tri-N-butylphosphine (0.18 mL, 0.73 mmol) at rt. The reaction was heated with microwave at 150 °C for 15 mm. The solvent was removed. The crude product waspurified by normal phase chromatography to provide Intermediate 155A (62 mg, 76percent) as a white solid. LC-MS(ESI) m/z: 339.0 [M+H].
  • 22
  • [ 194152-05-1 ]
  • [ 98-59-9 ]
  • [ 944563-27-3 ]
YieldReaction ConditionsOperation in experiment
77% With trimethylamine hydrochloride; triethylamine; In dichloromethane; at 20℃; A mixture of <strong>[194152-05-1]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide</strong> (660 mg, 4.39 mmol), 4- methylbenzenesulfonyl chloride (922 mg, 4.83 mmol), TEA (920 p1., 6.6 mmol), trimethylamine hydrochloride (42.0 mg, 439 pmol) in DCM ( 5.4 mL) was stirred at RT until complete conversion. DCM and water were added and the layers separated. The organic layer was evaporated to dryness under reduced pressure and the residue was purified by column chromatography to give 1 .03 g (77percent yield) of the title compound.1H NMR (400 MHz, DMSO-d6) oe [ppm] 0.16 - 0.84 (m, 1 H) 1.99 - 2.18 (m, 4 H) 2.43 (s, 3 H) 3.01 - 3.24 (m, 4 H) 4.83 (dt, 1 H) 7.49 (d, 2 H) 7.85 (d, 2 H).
  • 23
  • [ 194152-05-1 ]
  • methyl 3-[(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)oxy]-5-(5-methyl-1,3-thiazol-2-yl)benzoate [ No CAS ]
  • 24
  • [ 194152-05-1 ]
  • 3-[(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)oxy]-5-(5-methyl-1,3-thiazol-2-yl)benzoic acid [ No CAS ]
  • 25
  • [ 194152-05-1 ]
  • 3-[(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)oxy]-5-(5-methyl-1,3-thiazol-2-yl)-N-{(1R)-1-[2-(trifluoromethyl)pyrimidin-5-yl]ethyl}benzamide [ No CAS ]
  • 26
  • [ 194152-05-1 ]
  • tert-butyl 4-([2-[(1,1-dioxothian-4-yl)oxy]-4-(trifluoromethyl)phenyl]methyl)piperazine-1-carboxylate [ No CAS ]
  • 27
  • [ 194152-05-1 ]
  • 4-[2-(piperazin-1-ylmethyl)-5-(trifluoromethyl)phenoxy]thiane-1,1-dione [ No CAS ]
  • 28
  • [ 194152-05-1 ]
  • N-(1-(4-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)oxy)-4-(trifluoromethyl)benzyl)piperazine-1-carbonyl)-1H-pyrazol-3-yl)acetamide [ No CAS ]
  • 29
  • [ 1003581-82-5 ]
  • [ 194152-05-1 ]
  • methyl 6-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)oxy)pyrazolo[1,5-a]pyridine-3-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
65% With tributylphosphine; 1,1'-azodicarbonyl-dipiperidine; In toluene; at 120℃; for 0.75h;Microwave irradiation; Methyl 6-hydroxypyrazoIo[i,5-aipyridine3-carboxyiate (0100 g, 0.520 mniol),4-hydroxvtetrahydro-2H-thiopyran 1.1 -dioxide (0.094 g. 062 mmol), and I ,i(azodicarbonyi)dipiperidine (0.328 g, 130 mmoi) were placed in a pressure vial. Then, anhydrous PhMe (4 rnL) and tri-Nbutyiphosphine (0325 rnL, 130 rnmoi) were added, and the reaction mixture was stirred at 120 °C under microwave irradiation for 45 mm,The reaction mixture Was quenched with MeOH (1 mL), diluted with EtOAc (50 mL), Celite was added, and solvent was removed under reduced pressure. The residue was purified by flash chromatography (solid loading, 0-100percent EtOAc/DCM gradient) to give methyl 6-(( 1,1 -dioxidotetrahydro-2H-thiopyran-4-yI)oxy)pyrazoio[ I ,5-a]pvridine-3- carboxylale (0.110 g, 65 percent yield) as a white solid. MS (ESI) m/z: 325.0 (M+]H)1. ?H-NMR: (500 MHz, DMSO-d6) ppm 8.84 (d, J=2.2 Hz, IH), 839 (s, 1H), 800 (ci, J=9.4 Hz, 11-1), 753 (dd, .J:9.6. 1.9 T-{z. IFI), 4.78 (qdri, .J::4.6 FIz. 1FI). 382 (s. 3H). 330 - 323 (m, 2H), 3.19 - 3.12 (m, 2H). 226 (q, J=5.4 Hz, 4H).
 

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Technical Information

Categories

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Chemical Structure| 116529-31-8

A161694 [116529-31-8]

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride

Similarity: 0.66