15424-38-1|N-Phenylanthracen-9-amine| Ambeed

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Quality Control of [ 15424-38-1 ] Purity: 98+% SDS Specification

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Product Details of [ 15424-38-1 ]

CAS No. :	15424-38-1
Formula :	C₂₀H₁₅N
M.W :	269.34
SMILES Code :	C12=CC=CC=C1C(NC3=CC=CC=C3)=C4C=CC=CC4=C2
MDL No. :	MFCD03093237
InChI Key :	VNXLMMFDPYSZKF-UHFFFAOYSA-N
Pubchem ID :	13777361

Safety of [ 15424-38-1 ]

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302-H315-H319-H335
Precautionary Statements:	P261-P305+P351+P338

Application In Synthesis of [ 15424-38-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 15424-38-1 ]

[ 15424-38-1 ] Synthesis Path-Downstream 1~32

1
[ 15424-38-1 ]
[ 105862-44-0 ]

References: [1]Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences,1958,vol. 247,p. 1208,1209,1210.
Annales de Chimie (Cachan, France),1961,vol. <13>6,p. 1161,1216.

2
[ 15424-38-1 ]
[ 105820-80-2 ]

References: [1]Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences,1958,vol. 247,p. 1208,1209,1210.
Annales de Chimie (Cachan, France),1961,vol. <13>6,p. 1161,1216.

3
[ 15424-38-1 ]
[ 94-36-0 ]
[ 105791-33-1 ]

References: [1]Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences,1958,vol. 247,p. 1208,1209,1210.
Annales de Chimie (Cachan, France),1961,vol. <13>6,p. 1161,1216.

Yield	Reaction Conditions	Operation in experiment
83.9%	With tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate; In cyclohexane; toluene; for 2h;Inert atmosphere; Reflux;	General procedure: Step 1: Synthesis of 3,5-dimethyl-N-phenylaniline (S2)Under nitrogen, in a 500ml three-necked round flask, add 15.7g (0.1mol) of bromobenzene, 13.3 g (0.11mol) 3,5-dimethylaniline, 0.57g (1.0mol%) Pd (dba)2 , 2.0 ml (1.0mol%) P(t-Bu)3 10% cyclohexane solution and 19.2g (0.2mol)NaO(t-Bu). Followed by addition of 250ml anhydrous toluene, to obtain a reaction solution. The said reaction solution under magnetic stirring in a 110deg.C oil bath was refluxed for 2h. Cool. Then the reaction solution was washed with water and an appropriate amount of 2-3 times after subjected to liquid separation, and the resulting organic phase was dried over anhydrous MgSO4, the organic solvent was removed by rotary evaporation to give crude product. The crude product was purified by silica gel (200-300 mesh, Qingdao Marine Chemical) column chromatography to give the product 16.1g, a yield of 81.6%.

6
[ 15424-38-1 ]
[ 380149-52-0 ]
N⁵,N^5'-di-anthracen-9-yl-3,3',N⁵,N^5'-tetraphenyl-[2,2']bithiophenyl-5,5'-diamine [ No CAS ]

References: [1]Chemical Communications,2001,p. 1628 - 1629.

7
[ 573-17-1 ]
[ 15424-38-1 ]
(anthracen-9-yl)(phenanthren-9-yl)phenylamine [ No CAS ]

References: [1]Journal of Chemical Research,2005,p. 558 - 560.

8
[ 1564-64-3 ]
[ 62-53-3 ]
[ 15424-38-1 ]

Yield	Reaction Conditions	Operation in experiment
86%	With tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; XPhos; In toluene; at 100 - 110℃; for 2h;Inert atmosphere;	(1) To mechanical agitation, thermometer, After replacing the three-port reaction flask in the condenser with nitrogen, Add intermediate 24a (100mmol) in sequence, Raw material 24b (95mmol), 300ml toluene, heated to reflux for 0.5h, Cool down to 70 - 80 C, Slowly add sodium tert-butoxide (150mmol), Pd2 (dba) 3 (0.25mmol), xphos (0.5mmol), After the system is stable, it is heated to 100 - 110 C for 2 hours. Reduce the temperature to 25 - 30 C, add 200ml of water, stir and separate with 100ml of toluene, and extract the aqueous phase once with 200ml of toluene. Separate the liquid, combine the organic phase, add 7g of anhydrous sodium sulfate to the organic phase, stir and dry, filter The organic phase is concentrated (-0.08-0.09MPa, 55-60 C ) so that Recrystallize with 60ml toluene, filter, 82 mmol of intermediate 24c was obtained with a yield of 86%.
70%	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; at 100℃; for 72h;Inert atmosphere; Sealed tube;	An oven-dried pressure tube was cooled under nitrogen and charged with 9-bromanthracene (0.5 g, 1.9 mmol), distilled aniline (0.26 mL, 2.9 mmol), NaOtBu (0.44 g, 3.8 mmol), Pd(OAc)2 (22 mg, 5 mol%) and P(tBu)3 (23 uL, 0.1 mmol). To this was added dry toluene (10 mL). The pressure tube was sealed under nitrogen and stirred at 100 C for 72 h. After 72 h, the pressure tube was cooled to rt and toluene was removed in vacuo. Subsequently, the reaction was quenched with water and the organic contents were extracted with chloroform. The combined extract was dried over anhyd Na2SO4 and filtered. The solvent was removed in vacuo and the crude product was subjected to silica gel column chromatography using CHCl3/pet.ether (5:95) as an eluent to yield pure 9-(N-phenylamino)anthracene as yellow crystalline solid (0.36 g, 70% yield); mp 145 C; IR (neat film) cm1 3392, 1601, 1499, 1421, 1355, 1307; 1H NMR (CDCl3, 500 MHz) d 5.99 (s,1H), 6.59 (d, J = 8.0 Hz, 2H), 6.78 (t, J = 6.8 Hz, 1H), 7.14(t, J = 7.4 Hz, 2H), 7.44-7.48 (m, 4H), 8.05 (d, J = 8.6 Hz,2H), 8.19 (d, J = 8.6 Hz, 2H), 8.41 (s, 1H); 13C NMR (CDCl3, 125 MHz) d 113.8, 118.4, 123.8, 125.3, 125.4, 125.8,128.7, 129.0, 129.2, 132.2, 132.4, 147.9; EI-MS+ m/z Calcdfor C20H15N 269.1204 [M+], found 269.1206.

References: [1]Journal of Organic Chemistry,2013,vol. 78,p. 4649 - 4664.
[2]Patent: CN111018722,2020,A .Location in patent: Paragraph 0175-0177.
[3]Organic electronics,2014,vol. 15,p. 3766 - 3772.
[4]Journal of Chemical Research,2005,p. 558 - 560.

9
[ 1564-64-3 ]
[ 103-84-4 ]
[ 15424-38-1 ]

References: [1]Journal of Chemical Research,2005,p. 558 - 560.

10
[ 866413-65-2 ]
[ 15424-38-1 ]
[ 948305-21-3 ]

References: [1]Chemical Communications,2005,p. 4098 - 4100.

11
[ 81-86-7 ]
[ 15424-38-1 ]
4-(phenyl anthracen-9-yl)amino-1,8-naphthalic anhydride [ No CAS ]

References: [1]Journal of Physical Chemistry B,2005,vol. 109,p. 5509 - 5517.

12
[ 15424-38-1 ]
[ 948309-27-1 ]

References: [1]Chemical Communications,2005,p. 4098 - 4100.

13
[ 15424-38-1 ]
(E)-3-(5-(7-(anthracen-9-yl(phenyl)amino)-9,9-diethyl-9H-fluoren-2-yl)thiophen-2-yl)-2-cyanoacrylic acid [ No CAS ]

References: [1]Chemical Communications,2005,p. 4098 - 4100.

14
[ 15424-38-1 ]
[ 96378-62-0 ]

References: [1]Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences,1958,vol. 247,p. 1208,1209,1210.
Annales de Chimie (Cachan, France),1961,vol. <13>6,p. 1161,1216.

15
[ 15424-38-1 ]
[ 96766-00-6 ]

References: [1]Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences,1958,vol. 247,p. 1208,1209,1210.
Annales de Chimie (Cachan, France),1961,vol. <13>6,p. 1161,1216.

16
[ 10386-84-2 ]
[ 15424-38-1 ]
4-bromo-4'-[N-(9-anthracenyl)-N-phenylamino]-2,2',3,3',5,5',6,6'-octafluoro-1,1'-biphenyl [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		In a nitrogen flow, 160 mg (0.282 mmol) of palladium bis (benzylideneacetone) and 170 mg (0.846 mmol) of tri-tert-butylphosphine were dissolved in 40 ml of toluene and then stirred for 15 minutes at room temperature. Then, 0.58 g (1.27 mmol) of 4,4'- [ F] [DIBROMO-2, 2',] 3, [3',] 5, 5', 6, [6'-OCTAFLUORO-1,] 1'-biphenyl dissolved in 50 ml of toluene was dropped into the mixture and it was stirred for 30 minutes. Furthermore, 0.34 g (1.27 mmol) of [N- (9-ANTHRACENYL)-] N-phenylamine was dissolved in 50 ml of toluene and was then dropped therein, followed by the addition of 0.18 g (1.91 mmol) of sodium tert-butoxide. Then, the mixture was heated and stirred for about 8 hours in an oil bath heated at [120C.] After returning the reaction solution to room temperature, 50 ml of water was added thereto and the resultant solution was then separated into an aqueous layer and an organic layer. Furthermore, the aqueous layer was extracted with toluene and ethyl acetate, and was then combined with the previous organic layer and dried with magnesium sulfate. The solvent was evaporated and then the residue was purified by silicagel-column chromatography (toluene : hexane = [1 :] 2) to obtain 0.55 g of [4-BROMO-4'-[N-(9-ANTHRACENYL)-N-] [PHENYLAMINO]-2,] 2', 3, 3', 5, 5', 6, [6'-OCTAFLUORO-1,] 1'- biphenyl.

References: [1]Patent: WO2004/20388,2004,A1 .Location in patent: Page 54-55.

17
[ 327061-54-1 ]
[ 15424-38-1 ]
[ 1255517-95-3 ]

References: [1]Journal of Organic Chemistry,2010,vol. 75,p. 8100 - 8111.

18
C₂₃H₁₈N₂O₂ [ No CAS ]
[ 15424-38-1 ]

References: [1]RSC Advances,2014,vol. 4,p. 44689 - 44691.

19
[ 15424-38-1 ]
[ 1042269-05-5 ]
C₅₅H₄₀N₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
63%	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; at 100℃; for 72h;Inert atmosphere; Sealed tube;	General procedure: An oven-dried pressure tube was cooled under nitrogen and charged with 9-bromanthracene (0.5 g, 1.9 mmol), distilled aniline (0.26 mL, 2.9 mmol), NaOtBu (0.44 g, 3.8 mmol), Pd(OAc)2 (22 mg, 5 mol%) and P(tBu)3 (23 uL, 0.1 mmol). To this was added dry toluene (10 mL). The pressure tube was sealed under nitrogen and stirred at 100 C for 72 h. After 72 h, the pressure tube was cooled to rt and toluene was removed in vacuo. Subsequently, the reaction was quenched with water and the organic contents were extracted with chloroform. The combined extract was dried over anhyd Na2SO4 and filtered. The solvent was removed in vacuo and the crude product was subjected to silica gel column chromatography using CHCl3/pet.ether (5:95) as an eluent to yield pure 9-(N-phenylamino)anthracene as yellow crystalline solid (0.36 g, 70% yield)

References: [1]Organic electronics,2014,vol. 15,p. 3766 - 3772.

20
[ 108-86-1 ]
[ 779-03-3 ]
[ 15424-38-1 ]

Yield	Reaction Conditions	Operation in experiment
80%	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; for 2h;Reflux;	The tri-butyl phosphine (4.4 ml of 1.0M toluene solution, 1.48g, 0 . 05mmol), palladium acetate (0.4g, 1 . 83mmol) butyl sodium (22.8g, 238mmol) added to the 9 - amino anthracene (35.3g, 183mmol) and bromobenzene (59.9g, 183mmol) in degassing toluene (500 ml) of the solution in a, and the mixture is heated to reflux 2 hours. The reaction mixture is cooled to room temperature, the toluene dilution and for via the diatomaceous earth filter. The filtrate diluted with water, and is extracted with toluene, and combined with the organic phase, and under the condition of vacuum evaporation. The residue through silica gel (heptane/dichloromethane) filter, and from the isopropanol in crystallization. To obtain 1 - 4 (39.3g, the theoretical value of 80%).
80%	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; for 2h;Reflux;	A solution of tri-tert-butylphosphine (4.4 mL of 1.0 M in toluene, 1.48 g, 0.05 mmol)Palladium acetate (0.4 g, 1.83 mmol)And sodium tert-butoxide (22.8 g, 238 mmol)Was added to 9-aminanthracene (35.3 g, 183 mmol)And bromobenzene (59.9 g, 183 mmol)In degassed toluene (500 mL)And the mixture was heated under reflux for 2 hours.The reaction mixture was cooled to room temperature,Diluted with toluene and filtered through diatomaceous earth.The filtrate was diluted with water,And extracted with toluene,And the organic phase is combined,It was evaporated under vacuum.The residue was filtered through silica gel (heptane / dichloromethane)And crystallized from isopropanol.A2 (39.3 g, 80% theoretical).

References: [1]Patent: CN106187944,2016,A .Location in patent: Paragraph 0053; 0054; 0055; 0056.
[2]Patent: CN106565720,2017,A .Location in patent: Paragraph 0051; 0052; 0053.

21
[ 109-04-6 ]
[ 15424-38-1 ]
C₂₅H₁₈N₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With palladium diacetate; sodium t-butanolate; In toluene; for 2h;Reflux;	The tri-butyl phosphine (4.4 ml of 1.0M toluene solution, 1.13g, 5 . 6mmol), palladium acetate (0.3g, 1 . 4mmol) butyl sodium (40.3g, 420mmol) added to the 1 - 4 (37.6g, 140mmol) and 2 - 1 (34.4g, 168mmol) in degassing toluene (500 ml) of the solution in a, and the mixture is heated to reflux 2 hours. The reaction mixture is cooled to room temperature, the toluene dilution and for via the diatomaceous earth filter. The filtrate diluted with water, and is extracted with toluene, and combined with the organic phase, and under the condition of vacuum evaporation. The residue through silica gel (heptane/dichloromethane) filter, and from the isopropanol in crystallization. The resulting solid 1 - 5 (46.3g, 134mmol) and NBS (28.6, 161mmol) is dissolved in DMF with chloroform (1:3, 60 ml) in the mixed solution of, the room temperature stirring 6 hours, water and dichloromethane is used for extraction, drying the organic phase, concentration and crystallization from isopropanol in the obtained intermediate A2 (47.6g, the theoretical value of 80%).
	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; for 2h;Reflux;	Tri-tert-butylphosphine (4.4 mL of 1.0 M in toluene, 1.13 g, 5.6 mmol)Palladium acetate (0.3 g,1.4 mmol) and sodium tert-butoxide (40.3 g, 420 mmol)Was added to A2 (37.6 g, 140 mmol)And 2-bromopyridine (34.4 g, 168 mmol)In degassed toluene (500 mL)And the mixture was heated under reflux for 2 hours.The reaction mixture was cooled to room temperature,Diluted with toluene and filtered through diatomaceous earth.The filtrate was diluted with water,And extracted with toluene,And the organic phase is combined,It was evaporated under vacuum.The residue was filtered through silica gel (heptane / dichloromethane)And crystallized from isopropanol.The resulting solid B2 (46.3 g, 134 mmol) and NBS (28.6, 161 mmol)Was dissolved in DMF and chloroform (1: 3, 60 mL)Of the mixed solution,Stir at room temperature for 6 hours,Add water and extract with methylene chloride,Drying the organic phase,Concentration and crystallization from isopropanol gave Intermediate C2 (47.6 g, 80% of theory).

References: [1]Patent: CN106187944,2016,A .Location in patent: Paragraph 0053; 0057; 0058.
[2]Patent: CN106565720,2017,A .Location in patent: Paragraph 0054; 0055; 0056.

22
[ 17135-78-3 ]
[ 15424-38-1 ]
C₃₄H₂₃N [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
85%	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; for 2h;Reflux;	Tri-tert-butylphosphine (3 mL of a 1.0 M solution in toluene, 7.32 mmol), palladium acetate (0.4 g, 1.83 mmol) and sodium tert- butoxide (52.7 g, 549 mmol) were added to 2- chloroanthracene ) And Intermediate A-1 (49.2 g, 183 mmol) in degassed toluene (500 mL) and the mixture was heated at reflux for 2 h. The reaction mixture was cooled to room temperature, diluted with toluene and filtered through celite. The filtrate was diluted with water and extracted with toluene, and the organic phases were combined and evaporated under vacuum. The residue is filtered through silica gel and recrystallized to give the target product TM1 (69.2 g, 85% yield).

References: [1]Patent: CN107353212,2017,A .Location in patent: Paragraph 0054; 0057; 0058; 0059.

23
[ 716-53-0 ]
[ 62-53-3 ]
[ 15424-38-1 ]

Yield	Reaction Conditions	Operation in experiment
85%	With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate; In toluene; for 2h;Reflux;	Tri-tert-butylphosphine (3 mL of a 1.0 M solution in toluene, 7.32 mmol), palladium acetate (0.4 g, 1.83 mmol) and sodium tert- butoxide (22.8 g, 238 mmol) were added to 9- chloroanthracene ) And aniline (17.0 g, 183 mmol) in degassed toluene (500 mL) and the mixture heated at reflux for 2 h. The reaction mixture was cooled to room temperature, diluted with toluene and passed through diatomsSoil filtration. The filtrate was diluted with water and extracted with toluene, and the organic phases were combined and carried under vacuum evaporation. This residue was filtered through silica gel and recrystallized to give Intermediate A-1 (41.8 g, yield 85%).

References: [1]Patent: CN107353212,2017,A .Location in patent: Paragraph 0052; 0053; 0054; 0055; 0056.

24
[ 15424-38-1 ]
C₂₆H₁₆BrN₃ [ No CAS ]
C₄₆H₃₀N₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate; In toluene; for 24h;Reflux;	Sub 1 (16.9 g, 100 mmol) andSub 2 (156 g, 50 mmol) was dissolved in toluene(Dba) 3 (3 g, 7 mmol), P (t-Bu) 3 (0.7 g, 3.5 mmol)NaOt-Bu (14.8 g, 150 mmol) was added and the mixture was refluxed for 24 hours. After the reaction was completed, the reaction mixture was extracted with ether and water. The organic layer was dried over MgSO 4 and concentrated. The resulting organic material was purified by silica gel column and recrystallized.

References: [1]Patent: KR101950255,2019,B1 .Location in patent: Paragraph 0083; 0086.

25
[ 2038-91-7 ]
[ 15424-38-1 ]
C₃₃H₂₃N [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
88%	With tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; XPhos; In toluene; at 100 - 110℃; for 2h;Inert atmosphere;	70(2) To the machine equipped with mechanical stirring, thermometer, After replacing the three-port reaction flask in the condenser with nitrogen, Add intermediate 24c (80mmol) in sequence, Intermediate 3 (85mmol), 300ml toluene, heated to reflux for 0.5h, Cool down to 70 - 80 C, Slowly add sodium tert-butoxide (120mmol), Pd2 (dba) 3 (0.2mmol), xphos (0.4mmol), After the system is stable, it is heated to 100 - 110 C for 2h. Reduce the temperature to 25 - 30 C, add 200ml of water, stir and separate with 100ml of toluene, and extract the aqueous phase once with 200ml of toluene. Separate the liquid, combine the organic phase, add 7g of anhydrous sodium sulfate to the organic phase, stir and dry, filter The organic phase was concentrated (-0.08 0.09MPa, 55 - 60C) until it could not come out. Filtration to obtain 70mmol intermediate 24d, yield 88%

References: [1]Patent: CN111018722,2020,A .Location in patent: Paragraph 0175; 0178-0179.

26
[ 15424-38-1 ]
C₄₆H₃₀BrNO [ No CAS ]

References: [1]Patent: CN111018722,2020,A .

27
[ 15424-38-1 ]
C₄₆H₂₈BrN [ No CAS ]
C₄₆H₂₈BrN [ No CAS ]

References: [1]Patent: CN111018722,2020,A .

28
[ 15424-38-1 ]
C₄₆H₂₆BrN [ No CAS ]

References: [1]Patent: CN111018722,2020,A .

29
[ 15424-38-1 ]
C₆₆H₄₀N₂ [ No CAS ]

References: [1]Patent: CN111018722,2020,A .

30
[ 15424-38-1 ]
C₄₆H₂₆BrN [ No CAS ]
C₆₆H₄₀N₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
85%	With tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; XPhos; In toluene; at 100 - 110℃; for 2h;Inert atmosphere;	(6) To be equipped with mechanical stirring, thermometer, After replacing the three-port reaction flask in the condenser with nitrogen, Add intermediate 24h (10mmol) in sequence, Intermediate 24c (11mmol), 100ml toluene, Heating to reflux for 0.5h, Cool down to 70-80 C , Slowly add sodium tert-butoxide (15mmol), Pd2 (dba) 3 (0.05mmol), x-phos (0.1mmol), after the system is stabilized, heated to 100 ~ 110 C for 2h. Reduce the temperature to 25-30 C, add 50ml water, 50ml toluene and stir to separate. The aqueous phase is extracted once with 100ml toluene, separate the liquid, combine the organic phase, add 5g anhydrous sodium sulfate and stir to dry After filtration, the organic phase was concentrated (-0.08 to 0.09 MPa, 55 to 60 C) until it did not come out. 20 ml of petroleum ether was added with stirring and filtered to obtain 7.3 g of compound 24 in 85% yield.

References: [1]Patent: CN111018722,2020,A .Location in patent: Paragraph 0175; 0186-0187.

31
[ 90-93-7 ]
[ 15424-38-1 ]
C₆₂H₆₉N₅⁽²⁺⁾*2Cl^(1-) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
77.2%		A mixture of 4,4′-bis(diethylamino)-benzophenone (3.0g, 9.3mmol), toluene (30mL), and phosphorus (V) oxychloride (4.2mL, 15.2mmol) was vigorously stirred at 25C for 1h. Subsequently, n-phenyl-9-anthramine (1.0g, 3.7mmol) was added to the mixture. The resulting solution was stirred for 24h at 105C and then cooled to room temperature. The settled mixture was extracted using CH2Cl2 and NaCl brine. The collected organic layers were dried over anhydrous MgSO4 and evaporated. The crude dye mixture was refluxed in an acetone/ethyl acetate (1:3, v/v) binary solvent at 80C for 3h. The final solid product was filtered out and dried at 80C under vacuum for 1 day. Yield: 2.73g, 77.2%; 1H NMR (DMSO-d6, ppm): δ=10.1 (1H, s), 8.22 (2H, d), 7.31 (26H, m), 3.60 (16H, d), 1.20 (24H, t); 13C NMR (DMSO-d6, ppm): δ=12.70, 44.81, 45.46, 112.65, 113.94, 114.54, 114.63, 124.83, 125.58, 126.08, 126.33, 126.77, 127.50, 127.75, 129.55, 130.21, 130.46, 130.96, 131.19, 131.84, 132.71, 133.57, 137.00, 138.97, 139.94, 146.9, 153.82, 154.77, 155.33, 168.85, 169.83, 175.85; MALDI-TOF: m/z 882.57 (100%, [M + H]+); Elemental analysis: Calcd. for C62H69N5Cl2: C,77.96; H, 7.28; N, 7.33%. Found: C, 77.77; H, 7.42; N, 7.52.

References: [1]Dyes and Pigments,2021,vol. 196.

32
[ 90-93-7 ]
[ 15424-38-1 ]
C₆₂H₆₉N₅O₁₂S₄⁽²⁺⁾*2Cl^(1-) [ No CAS ]

References: [1]Dyes and Pigments,2021,vol. 196.

Historical Records

Technical Information

• Benzylic Oxidation • Birch Reduction • Blanc Chloromethylation • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Chan-Lam Coupling Reaction • Friedel-Crafts Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Leuckart-Wallach Reaction • Mannich Reaction • Petasis Reaction • Preparation of Alkylbenzene • Preparation of Amines • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Specialized Acylation Reagents-Vilsmeier Reagent • Ugi Reaction • Vilsmeier-Haack Reaction

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[ 15424-38-1 ]

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Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

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CAS No.: 15424-38-1

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