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Chemical Structure| 14156-95-7 Chemical Structure| 14156-95-7

Structure of 14156-95-7

Chemical Structure| 14156-95-7

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Product Citations

Product Citations

Li, Bowen ; Manan, Rajith Singh ; Liang, Shun-Qing ; Gordon, Akiva ; Jiang, Allen ; Varley, Andrew , et al.

Abstract: The expanding applications of nonviral genomic medicines in the lung remain restricted by delivery challenges. Here, leveraging a high-throughput platform, we synthesize and screen a combinatorial library of biodegradable ionizable lipids to build inhalable delivery vehicles for mRNA and CRISPR-Cas9 gene editors. Lead lipid nanoparticles are amenable for repeated intratracheal dosing and could achieve efficient gene editing in lung epithelium, providing avenues for gene therapy of congenital lung diseases.

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Product Details of [ 14156-95-7 ]

CAS No. :14156-95-7
Formula : C8H18N2
M.W : 142.24
SMILES Code : CC1CCN(CCN)CC1
MDL No. :MFCD00129007
InChI Key :BTEYOILJVIONOI-UHFFFAOYSA-N
Pubchem ID :783700

Safety of [ 14156-95-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P305+P351+P338
 

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[ 14156-95-7 ]

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