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Chemical Structure| 1937-19-5 Chemical Structure| 1937-19-5
Chemical Structure| 1937-19-5

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Aminoguanidine HCl is a selective and irreversible iNOS inhibitor.

Synonyms: Pimagedine hydrochloride; GER-11; Guanylhydrazine hydrochloride

4.5 *For Research Use Only !

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Product Details of Aminoguanidine HCl

CAS No. :1937-19-5
Formula : CH7ClN4
M.W : 110.55
SMILES Code : NNC(N)=N.[H]Cl
Synonyms :
Pimagedine hydrochloride; GER-11; Guanylhydrazine hydrochloride
MDL No. :MFCD00039074
InChI Key :UBDZFAGVPPMTIT-UHFFFAOYSA-N
Pubchem ID :2734687

Safety of Aminoguanidine HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Aminoguanidine HCl

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1937-19-5 ]

[ 1937-19-5 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 21221-93-2 ]
  • [ 1937-19-5 ]
  • 3,5-Bis-(trifluormethyl)-benzophenon-guanylhydrazon [ No CAS ]
  • 2
  • [ 342-25-6 ]
  • [ 1937-19-5 ]
  • 4,2'-Difluor-benzophenon-guanylhydrazon [ No CAS ]
  • 3
  • [ 2011-66-7 ]
  • [ 1937-19-5 ]
  • [ 136623-22-8 ]
  • 4
  • [ 16611-67-9 ]
  • [ 1937-19-5 ]
  • [ 146470-09-9 ]
  • 5
  • [ 66-39-7 ]
  • [ 1937-19-5 ]
  • [ 102451-50-3 ]
  • 6
  • [ 30263-65-1 ]
  • [ 1937-19-5 ]
  • [ 937-02-0 ]
  • 6-<i>tert</i>-butyl-[1,2,4]triazin-3-ylamine [ No CAS ]
  • 7
  • [ 1937-19-5 ]
  • [ 25847-32-9 ]
  • [ 937-02-0 ]
  • 6-<i>tert</i>-butyl-[1,2,4]triazin-3-ylamine [ No CAS ]
  • 8
  • [ 4126-60-7 ]
  • [ 1937-19-5 ]
  • [ 1315607-28-3 ]
  • 9
  • [ 2040-05-3 ]
  • [ 1937-19-5 ]
  • (E)-2-(1-(2,6-dichlorophenyl)ethylidene)hydrazinecarboximidamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
12% With sulfuric acid; In ethanol;Reflux; <strong>[2040-05-3]1-(2,6-dichlorophenyl)ethanone</strong> (373 mg, 1.97 mmol) and aminoguanidine hydrochloride (218 mg, 1.97 mmol) were refluxed in 10 ml EtOH with 78 ul of concentrated H2SO4 for 3 h. The reaction mixture was neutralized with 1N NaOH to PH=13. The solvent was evaporated and the residue was purified by silica gel chromatography using DCM/MeOH/NH3. H2O, to obtain the title compound as a white powder (12percent yield). 1H NMR (600 MHz, cd3od) delta 7.39 (d, J=7.9 Hz, 2H), 7.30 (t, J=8.0 Hz, 1H), 2.18 (s, 3H). 13C NMR (151 MHz, cd3od) delta 159.47, 147.37, 137.15, 132.11, 129.84, 127.75, 21.20. ESI-HRMS Calc m/z (M+H)+ Calc m/z 245.0355 Found 245.0359. HPLC 95.25percent purity tR=5.11 min.
  • 10
  • [ 175711-83-8 ]
  • [ 1937-19-5 ]
  • (E)-2-(1-(4-chloro-2-fluorophenyl)ethylidene)hydrazine-1-carboximidamide [ No CAS ]
 

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