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Chemical Structure| 6500-37-4 Chemical Structure| 6500-37-4

Structure of 6500-37-4

Chemical Structure| 6500-37-4

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Product Citations

Product Citations

Ashraf, Muhammad Awais ; Lee, Yunjeong ; Iqbal, Naila ; Iqbal, Naeem ; Cho, Eun Jin ;

Abstract: Trifluoromethylated mols. have gained privileged recognition among the medicinal and pharmaceutical chemists. Sustainable photoredox- and electrochem. processes were employed to facilitate the relatively less explored radical cross-electrophile coupling to access trifluoromethyl- and allyl-substituted tert-alcs. I (Ar = Ph, 2-ClC6H4, 2-naphthyl, etc.). Reactions proceed through trifluoromethyl ketyl radical and allyl radical intermediates, which underwent challenging radical-radical cross-coupling. The developed transformations are mild and chemo-selective to give cross-coupled products and deliver a wide range of valuable trifluoromethyl- and allyl-containing tertiary alcs. Both processes can also be applied for the synthesis of amine variant containing trifluoromethyl and allyl moiety, which is considered as amide bioisostere.

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Product Details of [ 6500-37-4 ]

CAS No. :6500-37-4
Formula : C12H7F3O
M.W : 224.18
SMILES Code : FC(F)(F)C(C1=C2C=CC=CC2=CC=C1)=O
MDL No. :MFCD01320007

Safety of [ 6500-37-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
 

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