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Chemical Structure| 2369-31-5 Chemical Structure| 2369-31-5

Structure of 2369-31-5

Chemical Structure| 2369-31-5

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Product Citations

Product Citations

Ashraf, Muhammad Awais ; Lee, Yunjeong ; Iqbal, Naila ; Iqbal, Naeem ; Cho, Eun Jin ;

Abstract: Trifluoromethylated mols. have gained privileged recognition among the medicinal and pharmaceutical chemists. Sustainable photoredox- and electrochem. processes were employed to facilitate the relatively less explored radical cross-electrophile coupling to access trifluoromethyl- and allyl-substituted tert-alcs. I (Ar = Ph, 2-ClC6H4, 2-naphthyl, etc.). Reactions proceed through trifluoromethyl ketyl radical and allyl radical intermediates, which underwent challenging radical-radical cross-coupling. The developed transformations are mild and chemo-selective to give cross-coupled products and deliver a wide range of valuable trifluoromethyl- and allyl-containing tertiary alcs. Both processes can also be applied for the synthesis of amine variant containing trifluoromethyl and allyl moiety, which is considered as amide bioisostere.

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Product Details of [ 2369-31-5 ]

CAS No. :2369-31-5
Formula : C14H9F3O
M.W : 250.22
SMILES Code : FC(F)(F)C(C1=CC=C(C2=CC=CC=C2)C=C1)=O
MDL No. :MFCD01320014

Safety of [ 2369-31-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P260-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338

Application In Synthesis of [ 2369-31-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2369-31-5 ]

[ 2369-31-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 2369-31-5 ]
  • [ 3883-39-4 ]
  • 2-([1,1'-biphenyl]-4-yl)-1,1,1-trifluoro-4-(5-methylpyridin-2-yl)butan-2-ol [ No CAS ]
  • 2
  • [ 13959-34-7 ]
  • [ 2369-31-5 ]
  • 2-([1,1'-biphenyl]-4-yl)-1,1,1-trifluoro-4-(4-methylpyridin-2-yl)butan-2-ol [ No CAS ]
 

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