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Chemical Structure| 580-15-4 Chemical Structure| 580-15-4
Chemical Structure| 580-15-4

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6-Aminoquinoline is an important quinoline derivative with broad applications in antimalarial and antimicrobial drug research. Derivatives like chloroquine and quinapyramine are used to treat malaria and certain parasitic infections. Additionally, 6-Aminoquinoline serves as a fluorescent probe and key intermediate for organic synthesis, used in DNA, RNA binding studies and the development of novel anti-infective drugs.

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Product Citations

Product Citations

Jang, Mingyeong ; Lim, Taeho ; Park, Byoung Yong ; Han, Min Su ;

Abstract: In this study, we developed a metal-free and highly chemoselective method for the reduction of aromatic nitro compounds. This reduction was performed using tetrahydroxydiboron [B2(OH)4] as the reductant and 4,4'-bipyridine as the organocatalyst and could be completed within 5 min at room temperature. Under optimal conditions, nitroarenes with sensitive functional groups, such as vinyl, ethynyl, carbonyl, and halogen, were converted into the corresponding anilines with excellent selectivity while avoiding the undesirable reduction of the sensitive functional groups.

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Product Details of 6-Aminoquinoline

CAS No. :580-15-4
Formula : C9H8N2
M.W : 144.17
SMILES Code : NC1=CC=C2N=CC=CC2=C1
MDL No. :MFCD00006803
InChI Key :RJSRSRITMWVIQT-UHFFFAOYSA-N
Pubchem ID :11373

Safety of 6-Aminoquinoline

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of 6-Aminoquinoline

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 580-15-4 ]
  • Downstream synthetic route of [ 580-15-4 ]

[ 580-15-4 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 580-15-4 ]
  • [ 176967-80-9 ]
References: [1] Journal fuer Praktische Chemie (Leipzig), 1906, vol. <2> 73, p. 249.
 

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