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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 1885-81-0 Chemical Structure| 1885-81-0

Structure of 1885-81-0

Chemical Structure| 1885-81-0

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Product Details of [ 1885-81-0 ]

CAS No. :1885-81-0
Formula : C7H4ClN
M.W : 137.57
SMILES Code : [C-]#[N+]C1=CC=C(Cl)C=C1
MDL No. :MFCD05664317

Safety of [ 1885-81-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H315-H319-H331-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P337+P313-P361-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 1885-81-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1885-81-0 ]

[ 1885-81-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 20781-20-8 ]
  • [ 1885-81-0 ]
  • [ 10165-86-3 ]
  • [ 501-52-0 ]
  • [ 947756-65-2 ]
YieldReaction ConditionsOperation in experiment
In trifluoroethanol; at 20℃; for 4h; Step A: Methyl 6-{2-[(4-chlorophenyl)amino]-1-[(2,4-dimethoxybenzyl)(3-phenylpropanoyl)-amino]-2-oxoethyl}nicotinate Dihydrocinnamic acid (46 mg, 0.30 mmol), 4-chlorophenylisocyanide (42 mg, 0.30 mmol) and 2,4-dimethoxybenzylamine (61 mg, 0.36 mmol) were added to a solution of methyl 6-formylnicotinate (see Langlois, Y. et al, Tetrahedron. 1975, 31, 419-22) (50 mg, 0.30 mmol) in 400 muL of TFE. The solution was allowed to stir for 4 h at room temperature and then purified by flash chromatography (12-100percent ethyl acetate in hexanes to give the desired product. MS cal'd 602 (MH+), exp 602 (MH+).
 

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