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Chemical Structure| 1521-51-3 Chemical Structure| 1521-51-3

Structure of 1521-51-3

Chemical Structure| 1521-51-3

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Product Details of [ 1521-51-3 ]

CAS No. :1521-51-3
Formula : C6H9Br
M.W : 161.04
SMILES Code : BrC1C=CCCC1
MDL No. :MFCD00013775
InChI Key :AJKDUJRRWLQXHM-UHFFFAOYSA-N
Pubchem ID :137057

Safety of [ 1521-51-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338
Class:3
UN#:1993
Packing Group:

Application In Synthesis of [ 1521-51-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1521-51-3 ]

[ 1521-51-3 ] Synthesis Path-Downstream   1~13

  • 1
  • [ 3337-66-4 ]
  • [ 1521-51-3 ]
  • 4-cyclohex-2-enyloxy-3,5-diiodo-benzoic acid methyl ester [ No CAS ]
  • 2
  • [ 932-32-1 ]
  • [ 1521-51-3 ]
  • [ 101195-45-3 ]
  • 3
  • [ 6940-80-3 ]
  • [ 1521-51-3 ]
  • (2S,3'R/S)-2-[N-benzyl-(cyclohexen-3'-yl)amino]propan-1-ol [ No CAS ]
  • 4
  • [ 16957-70-3 ]
  • [ 1521-51-3 ]
  • [ 55894-37-6 ]
  • 2-(2-cyclohexenyl)-2-methyl-3-pentenoic acid [ No CAS ]
  • (2E)-4-(2-cyclohexenyl)-2-methyl-2-pentenoic acid [ No CAS ]
  • 5
  • [ 1521-51-3 ]
  • [ 213135-39-8 ]
  • [ 2368-53-8 ]
  • 1,3-dichloro-5-cyclohex-2-enyl-2,4,6-trifluoro-benzene [ No CAS ]
  • 6
  • [ 20651-67-6 ]
  • [ 1521-51-3 ]
  • 1-(n-butyl)-4-(2-cyclohexenyl)benzene [ No CAS ]
  • 7
  • [ 50820-65-0 ]
  • [ 1521-51-3 ]
  • [ 774213-78-4 ]
YieldReaction ConditionsOperation in experiment
52% A solution (0.2 M) of methyl LH-INDOLE-6-CARBOXYLATE in DMF was cooled to 0 C then treated with LiH (1.3 eq. ). The mixture was stirred for 0.5 h then warmed to 20 C. A solution (1.0 M) of 3-BROMOCYCLOHEX-L-ENE (1.5 eq. ) in DMF was added and the mixture was stirred for 16 h. AcOEt and H20 were added and the organic layer was separated then washed with aqueous HCl (1 N) and dried. Removal of the solvent gave a residue that was purified by flash chromatography on silica gel (5: 95 ACOET/PETROLEUM ether) to afford the title compound (52%) as an oil. 'H NMR (300 MHz, CDCl3, 300 K) õ 1.61-1. 85 (m, 4H), 2.05-1. 18 (m, 2H), 3.71- 3.75 (m, 1H), 3.94 (s, 3H), 5.80-5. 95 (m, 2H), 7.14 (s, 1H), 7.67 (d, J 8.4 Hz, 1H), 7. 80 (d, J 8. 4 Hz, 1H), 8.12 (s, 1H), 8. 20 (br s, 1H); MS (ES+) m/z 256 (M+I+.
  • 8
  • [ 19745-07-4 ]
  • [ 1521-51-3 ]
  • [ 1233493-45-2 ]
  • 9
  • [ 1521-51-3 ]
  • [ 5270-94-0 ]
  • 2-(cyclohex-2-en-1-yl)-4,6-dimethoxypyrimidine [ No CAS ]
  • 10
  • [ 253-66-7 ]
  • [ 1521-51-3 ]
  • [ 1562367-34-3 ]
  • 11
  • [ 1521-51-3 ]
  • [ 3433-74-7 ]
  • 5-(cyclohex-2-en-1-yl)-5,11-dihydrodibenzo[b,e][1,4]oxazepine [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% To a solution of <strong>[3433-74-7]5,11-dihydrodibenzo[b,e][1,4]oxazepine</strong> (4.37 g, 22.1 mmol) in DMF (22 mL) at RT, was added NaH (0.975 g, 24.4 mmol, 60% dispersion in mineral oil). The mixture was stirred at RT for 20 min. 3-bromocyclohex-1-ene (7.12 g, 44.2 mmol) was added to the above solution at RT, and the reaction mixture was stirred for 3 h, neutralized with sat. aq. NH4CI, extracted with dichloromethane, concentrated in vacuo to give a residue which was purified by flash chromatography (SiO2, 0%-5% ethylacetate in hexanes) to afford 5-(cyclohex-2-en-1-yl)-<strong>[3433-74-7]5,11-dihydrodibenzo[b,e][1,4]oxazepine</strong> (5.08 g, 83%). 1H MR (600 MHz, CDCI3) delta 7.26-7.23 (1H, m), 7.17-7.14 (3H, m), 7.06-7.04 (1H, m), 6.97-6.94 (1H, m), 6.89-6.87 (1H, m), 6.77-6.74 (1H, m), 5.99-5.98 (1H, m), 5.71 (1H, d, J= 10.2 Hz), 4.58 (1H, d, J= 14.4 Hz), 4.35-4.32 (2H, m), 2.16-2.06 (2H, m), 1.97-1.86 (2H, m), 1.70- 1.65 (2H, m); 13C NMR (150 MHz, CDC13) delta 157.8, 147.5, 141.0, 131.9, 131.2, 129.7, 128.7, 128.1, 124.4, 123.7, 122.1, 120.1, 119.6, 118.2, 56.9, 48.6, 26.9, 25.2, 21.6; LCMS m/z 278.3577 ([M + H+], C19H20NO requires 278.3677).
  • 12
  • [ 230299-21-5 ]
  • [ 1521-51-3 ]
  • 2-((R)-cyclohex-2-en-1-yl)-4,4,6-trimethyl-1,3,2-dioxaborinane [ No CAS ]
  • 13
  • [ 6277-17-4 ]
  • [ 1521-51-3 ]
  • C13H15NO2 [ No CAS ]
 

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Technical Information

Categories

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[ 1521-51-3 ]

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