Home Cart Sign in  
Chemical Structure| 1173-43-9 Chemical Structure| 1173-43-9

Structure of 1173-43-9

Chemical Structure| 1173-43-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1173-43-9 ]

CAS No. :1173-43-9
Formula : C21H11NO5S
M.W : 389.38
SMILES Code : O=C(O)C1=CC(N=C=S)=CC=C1C2=C3C=CC(C=C3OC4=C2C=CC(O)=C4)=O

Safety of [ 1173-43-9 ]

Application In Synthesis of [ 1173-43-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1173-43-9 ]

[ 1173-43-9 ] Synthesis Path-Downstream   1~3

  • 1
  • inulin multi-methacrylate [ No CAS ]
  • α-(2-methoxy-5-isothiocyanatophenyl)-1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid [ No CAS ]
  • [ 1173-43-9 ]
  • [ 7446-81-3 ]
  • N-(3-aminopropyl)methacrylamide hydrochloride [ No CAS ]
  • FITC-labeled Gd-DOTA-containing articles [ No CAS ]
YieldReaction ConditionsOperation in experiment
100% Using reverse microemulsion techniques, nanoarticles were made with APMA containing free amines that can react with the isothiocyanate moiety of the MeODOTA chelator and/or of fluorescein isothiocyanate (FITC). These APMA-containing articles (comprising IMMA/APMA/NaA in the ratio 14: 2: 1) were dissolved in 0.1 M bicarbonate buffer, pH 9.4 at 65 mg/mL. A two-fold excess of MeODOTA-NCS/HCI and 1 mg of FITC were added and allowed to react for 1.5 hours. Unreacted MeODOTA and FITC were removed by size exclusion chromatography (PD-10 column equilibrated with water). One equivalent of gadolinium chloride (GdCl3) was added directly to the DOTA-containing articles in water and was allowed to chelate for 4 hours at 50°C. Unchelated gadolinium was removed by size exclusion chromatography. The FITC-labeled Gd-DOTA-containing articles were lyophilized to quantitate yield. Ligand attachment, if desired, follows.
  • 2
  • L-Lys(Dde)-OH [ No CAS ]
  • [ 133-32-4 ]
  • Fmoc-Cys(Trt)(Wang Resin LL)-resin [ No CAS ]
  • [ 2418-95-3 ]
  • [ 2799-07-7 ]
  • [ 1173-43-9 ]
  • [ 3057-74-7 ]
  • [ 56-40-6 ]
  • amino-PEG(2u)-acid [ No CAS ]
  • [ 147-85-3 ]
  • (S)-2-amino-5-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)pentanoic acid [ No CAS ]
  • C94H129N21O28S3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
40% The IBA-iRGD molecule was synthesized using standard solid phase synthesis protocols on a Fmoc-Cys(Trt)Wang Resin and Fmoc chemistry as described above. The following residues were coupled in order: Asp(OtBu), Pro, Gly, Lys(Boc), Asp(OtBu), Gly, Arg(Pbf), Cys(Trt), N-amido-dPEG2-acid, Lys(ivDde), N-amido-dPEG2-acid, Lys(Boc), mBA. The ivDde protecting group was removed by 2percent hydrazine in DMF. FITC was allowed to react for 3 h in DMF. The molecule was then cleaved from the resin in 92.5percent TFA, 2.5percent TIS, 2.5percent EDT and 2.5percent DI. water, purified via RP-HPLC on a Zorbax C18 column, and characterized using MALDI-TOF MS (FIG. 13). The peptide was cyclized overnight in DMF with DIEA and cyclization was verified via MALDI-TOF MS. The yield was 40percent, and product purity was confirmed using RP-HPLC on an analytical Zorbax C18 colunm to be >95percent.
  • 3
  • [ 1173-43-9 ]
  • [ 120068-37-3 ]
  • 5-(3-(3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1H-pyrazol-5-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
49% With triethylamine; In N,N-dimethyl-formamide; at 40℃; Fluorescein isothiocyanate (78 mg, 0.20 mmol), <strong>[120068-37-3]fipronil</strong> (175 mg, 0.40 mmol), and triethylamine (100 mL, 0.72 mmol) were dissolved in anhydrous DMF (3 mL) and stirred overnight at 40C. The crude product was purified by preparative HPLC to give compound 3 as an orange powder. 1H NMR (MeOD, 400 MHz) delta: 8.18 (s, 1H, Ar-H), 8.12 (s, 2H, Ar-H), 7.81 (d, J = 8.5 Hz, 1H, Ar-H), 7.22 (d, J = 8.5 Hz, 1H, Ar-H), 6.92-6.76 (br s, 4H, Ar-H), 6.69 (br d, 2H, Ar-H) ppm. ESI mass spectrometry: m/z = 827.8 [M+H]+.
 

Historical Records