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Chemical Structure| 10340-91-7 Chemical Structure| 10340-91-7

Structure of 10340-91-7

Chemical Structure| 10340-91-7

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Product Details of [ 10340-91-7 ]

CAS No. :10340-91-7
Formula : C8H7N
M.W : 117.15
SMILES Code : [C-]#[N+]CC1=CC=CC=C1
MDL No. :MFCD00000004
InChI Key :RIWNFZUWWRVGEU-UHFFFAOYSA-N
Pubchem ID :82558

Safety of [ 10340-91-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H315-H319-H331-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P337+P313-P361-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 10340-91-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10340-91-7 ]

[ 10340-91-7 ] Synthesis Path-Downstream   1~13

  • 1
  • [ 10340-91-7 ]
  • [ 119479-32-2 ]
  • [ 78-84-2 ]
  • cinnamyl amine resin [ No CAS ]
  • [1-(1-benzylcarbamoyl-2-methyl-propyl)-2-oxo-2,3,4,7-tetrahydro-1<i>H</i>-azepin-3-yl]-carbamic acid <i>tert</i>-butyl ester [ No CAS ]
  • 2
  • [ 10340-91-7 ]
  • [ 119479-32-2 ]
  • [ 100-52-7 ]
  • cinnamyl amine resin [ No CAS ]
  • [1-(benzylcarbamoyl-phenyl-methyl)-2-oxo-2,3,4,7-tetrahydro-1<i>H</i>-azepin-3-yl]-carbamic acid <i>tert</i>-butyl ester [ No CAS ]
  • 3
  • [ 104-53-0 ]
  • [ 10340-91-7 ]
  • [ 119479-32-2 ]
  • cinnamyl amine resin [ No CAS ]
  • [1-(1-benzylcarbamoyl-3-phenyl-propyl)-2-oxo-2,3,4,7-tetrahydro-1<i>H</i>-azepin-3-yl]-carbamic acid <i>tert</i>-butyl ester [ No CAS ]
  • 4
  • [ 98-01-1 ]
  • [ 6214-35-3 ]
  • [ 10340-91-7 ]
  • [ 2393-23-9 ]
  • C24H23IN2O4 [ No CAS ]
  • 5
  • [ 98-01-1 ]
  • [ 6214-35-3 ]
  • [ 10340-91-7 ]
  • [ 141-43-5 ]
  • C18H19IN2O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
77% In methanol; at 50℃; for 24h; To a stirred solution of 2-aminoethanol (44, 0.049 mL, 0.82 mmol) in MeOH (2.3 mL) at r.t. were added 2-furfural (8, 0.120 mL, 1.23 mmol), <strong>[6214-35-3](Z)-3-iodoacrylic acid</strong> [(Z)-6, 162 mg, 0.82 mmol],28 and benzyl isocyanide (7, 0.923 mL, 7.58 mmol). After stirring at 50 C for 24 h, the mixture was concentrated under reduced pressure. The residue was purified by column chromatography (silica gel, 15 g, hexane-EtOAc, 7:3) to give 45 (279 mg, 77%) as a brown foam.
  • 6
  • [ 1074-12-0 ]
  • [ 10340-91-7 ]
  • [ 24835-08-3 ]
  • [ 65-85-0 ]
  • [ 1616367-11-3 ]
  • 7
  • [ 1074-12-0 ]
  • [ 10340-91-7 ]
  • [ 24835-08-3 ]
  • [ 88-65-3 ]
  • [ 1616367-13-5 ]
  • 8
  • [ 10340-91-7 ]
  • [ 2033-42-3 ]
  • [ 70-11-1 ]
  • (1-(benzylamino)naphtho[2,1-b]furan-2-yl)(phenyl)methanone [ No CAS ]
  • 9
  • [ 40263-57-8 ]
  • [ 10340-91-7 ]
  • [ 70-11-1 ]
  • (3-(benzylamino)furo[3,2-b]pyridin-2-yl)(phenyl)methanone [ No CAS ]
  • 10
  • [ 10340-91-7 ]
  • [ 52562-19-3 ]
  • [ 81102-84-3 ]
YieldReaction ConditionsOperation in experiment
50% With copper diacetate; palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,2-bis-(diphenylphosphino)ethane; In acetonitrile; at 100℃; for 0.24h;Sealed tube; General procedure: General procedure for the palladium-catalyzed intermolecularoxidative cyclization of 2-vinylanilines with isocyanides to thesynthesis of 2-aminoquinolines: A mixture of 2-vinylaniline 1(0.2 mmol) and isocyanide 2 (0.4 mmol, 2.0 equiv), Pd(OAc)2(10 mol %), dppe (20 mol %), Cu(OAc)2 (0.4 mmol, 2.0 equiv), DBU(0.4 mmol, 2.0 equiv), and CH3CN (2 mL) were added into a sealedtube. The mixture was stirred at 100 C or about 24 h (monitored byTLC). After being cooling to room temperature, evaporation of thesolvent under reduced pressure followed purication by silica gel chromatography using petroleum ether/ethyl acetate (20:1 to 10:1)as eluent to provide the desired products 3.
  • 11
  • [ 590-92-1 ]
  • [ 1074-12-0 ]
  • [ 10340-91-7 ]
  • [ 24835-08-3 ]
  • 5-benzoyl-5-(N-benzylcarbamoyl)-1-(2-nitrobenzyl)-2-pyrrolidinone [ No CAS ]
  • 12
  • [ 10340-91-7 ]
  • [ 14847-51-9 ]
  • 7-methyl-2,3-diphenylbenzofuro[2,3-b]pyrazine [ No CAS ]
  • 13
  • [ 13884-13-4 ]
  • [ 3382-18-1 ]
  • [ 10340-91-7 ]
  • N-benzyl-2-(1H-indole-1-carbonyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
56% In methanol; dichloromethane; at 0℃; for 24h;Inert atmosphere; In a dry two-necked reaction flask33 mg (0.2 mmol) of N-indolecarboxylic acid and 46 mg (0.24 mmol) of 6,7-dimethoxy-3,4-dihydroisoquinoline were weighed in, and 2 mL of a solvent (dichloromethane: (Methanol = 1: 2), followed by injection of 28 mg of benzyl isonitrile, and the reaction was stirred in an ice water bath for 24 hours. The reaction conversion was detected by TLC.After adding silica gel for sample stirring, column chromatography (eluent: petroleum ether: ethyl acetate = 5: 1) yielded 53 mg of the product with a yield of 56%. The reaction is as follows:
 

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