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Chemical Structure| 1006-64-0 Chemical Structure| 1006-64-0

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Chemical Structure| 1006-64-0

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Product Details of [ 1006-64-0 ]

CAS No. :1006-64-0
Formula : C10H13N
M.W : 147.22
SMILES Code : C1CNC(C1)C1=CC=CC=C1
MDL No. :MFCD01631835
InChI Key :JUTDHSGANMHVIC-UHFFFAOYSA-N
Pubchem ID :261892

Safety of [ 1006-64-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 1006-64-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1006-64-0 ]

[ 1006-64-0 ] Synthesis Path-Downstream   1~35

  • 1
  • [ 132959-49-0 ]
  • [ 1006-64-0 ]
  • 2
  • [ 882-33-7 ]
  • [ 1006-64-0 ]
  • 3
  • (S)-3-Methyl-2-((S)-2-phenyl-pyrrolidin-1-yl)-butyric acid methyl ester [ No CAS ]
  • [ 1006-64-0 ]
  • 5
  • [ 79-37-8 ]
  • [ 1006-64-0 ]
  • 1,2-Bis-((S)-5-phenyl-pyrrolidin-3-yl)-ethane-1,2-dione [ No CAS ]
  • 7
  • [ 1006-64-0 ]
  • [ 99-33-2 ]
  • 2-phenyl-N-(3,5-dinitrobenzoyl)-pyrrolidine [ No CAS ]
  • 8
  • [ 106-39-8 ]
  • [ 1006-64-0 ]
  • (S)-N-(4-chlorophenyl)-2-phenylpyrrolidine [ No CAS ]
  • 9
  • [ 92-66-0 ]
  • [ 1006-64-0 ]
  • 1-Biphenyl-4-yl-2-phenyl-pyrrolidine [ No CAS ]
  • 10
  • (S)-ethyl 2-(2-phenylpyrrolidin-1-yl)-2-oxoacetate [ No CAS ]
  • [ 1006-64-0 ]
  • 11
  • [ 39637-99-5 ]
  • [ 1006-64-0 ]
  • C20H20F3NO2 [ No CAS ]
  • 12
  • [ 20445-33-4 ]
  • [ 1006-64-0 ]
  • (2S)-2-phenylpyrrolidine-(S)-MTPA-amide [ No CAS ]
  • 13
  • [ 350479-90-2 ]
  • [ 1006-64-0 ]
  • 14
  • [ 316813-41-9 ]
  • [ 1006-64-0 ]
  • 15
  • [ 316813-68-0 ]
  • [ 1006-64-0 ]
  • 16
  • [ 316813-12-4 ]
  • [ 1006-64-0 ]
  • 17
  • [ 316813-66-8 ]
  • [ 1006-64-0 ]
  • 18
  • [ 316813-29-3 ]
  • [ 1006-64-0 ]
  • 19
  • [ 316813-33-9 ]
  • [ 1006-64-0 ]
  • 20
  • 4-methyl-benzenesulfinic acid (2-benzenesulfonyl-1-phenyl-but-3-enyl)-amide [ No CAS ]
  • [ 1006-64-0 ]
  • 21
  • [ 1006-64-0 ]
  • 1,2-Bis(S)-(2-phenylpyrrolidinyl)ethane [ No CAS ]
  • 22
  • [ 174311-01-4 ]
  • [ 1006-64-0 ]
  • 23
  • Methanesulfinic acid 3-(benzyl-tert-butoxycarbonyl-amino)-propyl ester [ No CAS ]
  • [ 1006-64-0 ]
  • 24
  • [ 56139-59-4 ]
  • [ 1006-64-0 ]
  • 25
  • [ 132959-45-6 ]
  • [ 1006-64-0 ]
  • 28
  • [ 796600-15-2 ]
  • [ 1006-64-0 ]
  • 2-chloro-3-methyl-4-(2-phenyl-pyrrolidin-1-yl)-benzonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
37% With 4-methyl-morpholine; at 150℃; Heat <strong>[796600-15-2]2-chloro-4-fluoro-3-methyl-benzonitrile</strong> (144 mg, 0.85 mmol) and 2- . phenyl-pyrrolidine (0.15 g, 1.02 mmol, 1.20 equivalents) in N-methylmorpholine (0.11 ml, 1.02 mmol, 1.20 equivalents) at 150 0C overnight. Allow the reaction mixture to cool to room temperature, dilute with dichloromethane (1 ml), load on silica, and purify by chromatography (12 g silica gel, 0 to 100% ethyl acetate/hexanes over 20 minutes) to obtain 150 mg of an oily residue. Recrystallize from ethyl acetate/hexanes to obtain the title compound (92 mg, 37%). LCMS(APCI+): 297.0 (M+l)+; 1H NMR (400 MHz, CDCl3): delta 7.25 (s, 2H), 7.19 (m, 2H), EPO <DP n="58"/>6.65 (d, IH), 4.70 (m, IH), 4.06 (m, IH), 3.18 (m, IH), 2.44 (m, IH), 2.43 (s, 3H), 2.12 (m, IH), 1.94 (m, 2H).
  • 29
  • [ 1179523-32-0 ]
  • [ 1006-64-0 ]
  • 30
  • [ 1207729-66-5 ]
  • [ 1006-64-0 ]
  • 31
  • (-)-(S)-2-Phenylpyrrolidine hydrochloride [ No CAS ]
  • [ 1006-64-0 ]
  • 34
  • [ 1294455-04-1 ]
  • [ 1006-64-0 ]
  • 35
  • [ 1294455-05-2 ]
  • [ 1006-64-0 ]
 

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Technical Information

Categories

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[ 1006-64-0 ]

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