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Chemical Structure| 39637-99-5 Chemical Structure| 39637-99-5

Structure of 39637-99-5

Chemical Structure| 39637-99-5

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Product Details of [ 39637-99-5 ]

CAS No. :39637-99-5
Formula : C10H8ClF3O2
M.W : 252.61
SMILES Code : ClC([C@@](C(F)(F)F)(OC)C1=CC=CC=C1)=O
MDL No. :MFCD00044400
InChI Key :PAORVUMOXXAMPL-VIFPVBQESA-N
Pubchem ID :3080792

Safety of [ 39637-99-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 39637-99-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 39637-99-5 ]

[ 39637-99-5 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 10482-56-1 ]
  • [ 39637-99-5 ]
  • (S,S)-α-methoxy-α-(((trifluoromethyl)phenyl)acetyl) ester (R)-terpineol [ No CAS ]
  • 2
  • [ 39637-99-5 ]
  • [ 137496-71-0 ]
  • (R)-3,3,3-Trifluoro-2-methoxy-1-((S)-2-methyl-pyrrolidin-1-yl)-2-phenyl-propan-1-one [ No CAS ]
  • 3
  • [ 39637-99-5 ]
  • [ 87860-35-3 ]
  • (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-2-phenoxy-propyl ester [ No CAS ]
  • 4
  • [ 39637-99-5 ]
  • [ 112018-26-5 ]
  • [ 111934-09-9 ]
  • 5
  • [ 39637-99-5 ]
  • [ 63060-94-6 ]
  • [ 121269-59-8 ]
  • 6
  • [ 2914-69-4 ]
  • [ 39637-99-5 ]
  • [ 133796-97-1 ]
  • 7
  • [ 56523-47-8 ]
  • [ 39637-99-5 ]
  • (2S)-2-phenylpyrrolidine-(S)-MTPA-amide [ No CAS ]
  • 8
  • [ 39637-99-5 ]
  • [ 1006-64-0 ]
  • C20H20F3NO2 [ No CAS ]
  • 9
  • [ 56523-47-8 ]
  • [ 39637-99-5 ]
  • (2R)-2-phenylpyrrolidine-(S)-MTPA-amide [ No CAS ]
  • 10
  • [ 613-87-6 ]
  • [ 39637-99-5 ]
  • (S)-1-phenylpropyl (S)-α-methoxy-α-trifluoromethylphenylacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine; dmap; In dichloromethane; at 20℃; for 16h; General procedure: To a stirred solution of the alcohol (15 mg), pyridine (0.1 mL), and 4,4-dimethylaminopyridine (1-2 crystals) in CH2Cl2 (0.5 mL) was injected (R)-MTPA chloride (25 mg) in CH2Cl2 (0.5 mL). After stirring the mixture for 16 h at room temperature, the excess pyridine was removed by purging with N2 gas, and the residue subjected to preparative thin-layer chromatography (silica gel, 10% EtOAc/hexane) to isolate the respective MTPA esters. The 1H NMR analyses were carried out with the pure samples. The MTPA esters of the racemic alcohols were also prepared as above and the diagnostic 1H NMR methoxyl resonances for them were as follows: 3b. 1H NMR: δ 3.37 and 3.50; 5b. 1H NMR: δ 3.40 and 3.49; 6b. 1H NMR: δ 3.40 and 3.48; 8b. 1H NMR: δ 3.40 and 3.49; 10b. 1H NMR: δ 3.39 and 3.48; 11b. 1H NMR: δ 3.46 and 3.59; 12b. 1H NMR: δ 3.45 and 3.59; 13b. 1H NMR: δ 3.46 and 3.56; 14b. 1H NMR: δ 3.45 and 3.55.
 

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Similar Product of
[ 39637-99-5 ]

Chemical Structure| 20445-33-4

A343152 [20445-33-4]

(S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoyl chloride

Reason: Optical isomers