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Chemical Structure| 17601-94-4 Chemical Structure| 17601-94-4
Chemical Structure| 17601-94-4
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Product Details of [ 17601-94-4 ]

CAS No. :17601-94-4
Formula : C7H4BrN3O2
M.W : 242.03
SMILES Code : NC1=C(C=C(C=C1Br)[N+]([O-])=O)C#N
MDL No. :MFCD00054185
Boiling Point : No data available
InChI Key :MUHLVSZIVTURCZ-UHFFFAOYSA-N
Pubchem ID :87173

Safety of [ 17601-94-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 17601-94-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17601-94-4 ]

[ 17601-94-4 ] Synthesis Path-Downstream   1~30

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  • 3
  • [ 68189-36-6 ]
  • [ 17601-94-4 ]
  • N-[5-[Bis-(2-hydroxy-ethyl)-amino]-2-(2-bromo-6-cyano-4-nitro-phenylazo)-phenyl]-propionamide [ No CAS ]
  • 4
  • [ 27905-38-0 ]
  • [ 17601-94-4 ]
  • N-[2-(2-Bromo-6-cyano-4-nitro-phenylazo)-5-dimethylamino-phenyl]-benzamide [ No CAS ]
  • 5
  • [ 17601-94-4 ]
  • [ 23128-51-0 ]
  • [ 87260-48-8 ]
  • 6
  • [ 17601-94-4 ]
  • [ 39240-08-9 ]
  • N-[2-(2-Bromo-6-cyano-4-nitro-phenylazo)-5-diethylamino-phenyl]-benzamide [ No CAS ]
  • 7
  • [ 17601-94-4 ]
  • [ 22185-75-7 ]
  • [ 85929-33-5 ]
  • 8
  • [ 17601-94-4 ]
  • [ 55911-12-1 ]
  • N-[2-(2-Bromo-6-cyano-4-nitro-phenylazo)-5-dimethylamino-phenyl]-propionamide [ No CAS ]
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  • [ 17601-94-4 ]
  • [ 76751-08-1 ]
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  • 11
  • [ 17601-94-4 ]
  • [ 76751-15-0 ]
  • Pentanoic acid [2-(2-bromo-6-cyano-4-nitro-phenylazo)-5-diethylamino-phenyl]-amide [ No CAS ]
  • 12
  • [ 17601-94-4 ]
  • [ 71673-07-9 ]
  • N-[2-(2-Bromo-6-cyano-4-nitro-phenylazo)-5-dipropylamino-phenyl]-benzamide [ No CAS ]
  • 13
  • [ 17601-94-4 ]
  • [ 24530-67-4 ]
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  • [ 42875-94-5 ]
  • [ 42875-90-1 ]
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  • [ 17601-94-4 ]
  • [ 24311-37-3 ]
  • [ 3618-70-0 ]
  • 16
  • [ 17601-94-4 ]
  • [ 121-69-7 ]
  • 3-Bromo-2-(4-dimethylamino-phenylazo)-5-nitro-benzonitrile [ No CAS ]
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  • [ 17601-94-4 ]
  • [ 91-66-7 ]
  • [ 87260-50-2 ]
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  • [ 19433-93-3 ]
  • [ 87260-49-9 ]
  • 20
  • [ 17601-94-4 ]
  • 2-bromo-6-cyano-p-phenylenediamine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium tetrahydroborate; copper(II) ion; at 60 - 65℃; for 0.166667h;Green chemistry; General procedure: The general procedure for the hydrogenation of nitro compounds is as follows: The three-neck round bottom flask equipped with a Teflon-coated condenser, thermopocket, and magnetic needle containing substrate (1 mmol) dissolved in methanol or water(1.2 mL) was stirred and heated at 60-65 C under atmospheric environment. To this clear-stirred solution, copper(II)salt (2 mol % of Cu(OAc)2 or CuCO3 or Cu(NO3)2 or 3 mol % of Cu(OH)2 or CuSO4 or 4 mol % of CuO or 6 mol% of CuCl2 catalyst, as per Table 3) was added. Sequentially portion-wise addition (each portion 0.25 equiv./min) of NaBH4 (2.0-2.5 molar ratio to the substrate, as per Table 2) was charged within10 min. With the instant addition of the first portion of NaBH4, black granular precipitate formation with concomitant (H2) gas evolution was observed. As per TLC confirmation, the starting material was consumed completely within 10 min. Upon reaction completion, the reaction mixture was then filtered to remove the parted black precipitates. Further to thus obtained filtered mixture, 10 mL water was added into the filtered solution. Now the product isolation method was reliant on the nature of the product obtained. Upon addition of water, if precipitation occurs in the case of the solid product, then the parted solid product was isolated upon simple filtration and dried, if not then the aqueous solution was extracted with EtOAc (5mL 2), the sequentially combined organic layer was washed with water (5mL 2) and dried over anhydrous sodium sulfate. After filtration, the solvent was removed under vacuo affording the desired amine. It was observed that the purity of the crude product was more than 99%by 1H NMR, henceforth, to obtain pure product no column or flash chromatographic separation technique was needed.
YieldReaction ConditionsOperation in experiment
Examples of Amines Useful in the Present Invention 2-chloro-4,6-dinitroaniline 2-bromo-4,6-dinitroaniline 2-chloro-6-cyano-4-nitroaniline 2-bromo-6-cyano-4-nitroaniline 2,6-dicyano-4-nitroaniline 2-cyano-4,6-dinitroaniline
  • 22
  • [ 124-38-9 ]
  • [ 17601-94-4 ]
  • 8-bromo-6-nitroquinazoline-2,4(1H,3H)-dione [ No CAS ]
  • 23
  • [ 17601-94-4 ]
  • [ 677298-30-5 ]
YieldReaction ConditionsOperation in experiment
89% With urea; 4-Amino-8-bromo-6-nitro-quinazolin-2-ol 2-Amino-3-bromo-5-nitro-benzonitrile (1.9003 g, 7.85 mmol) was heated with urea (1.8862 g, 31.4 mmol) at 180-185 C. for 3 hrs. The cooled mixture was powered and treated with bicarbonate solution, filtered and washed with water. The solid was the collected and washed with ethanol, ether, and used for the next step reaction without further purification. 2.0 g product was obtained. Yield 89%; 1H NMR (500 MHz, DMSO-d6): δ 8.44455-8.45011 (d, J=2.78 Hz, 1H), 8.87071-8.87544 (d, J=2.365 Hz, 1H), 9.39866-9.40333 (d, J=2.335 Hz, 1H), 9.50740-9.51282 (d, J=2.71 Hz, 1H); ESI-MS: 285, 287 (M++1)
  • 24
  • [ 17601-94-4 ]
  • 6-bromo-2-cyano-N,N'-bisphenylthio-benzoquinone diimine [ No CAS ]
 

Historical Records

Technical Information

Categories

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[ 17601-94-4 ]

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