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Chemical Structure| 142-47-2 Chemical Structure| 142-47-2
Chemical Structure| 142-47-2

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L-Glutamic Acid Monosodium is an excitatory amino acid neurotransmitter as an agonist at GluR and NMDA receptor.

Synonyms: Monosodium glutamate; MSG; Sodium glutamate

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Product Details of H-Glu-OH(Sodium)

CAS No. :142-47-2
Formula : C5H8NNaO4
M.W : 169.11
SMILES Code : O=C([O-])[C@@H](N)CCC(O)=O.[Na+]
Synonyms :
Monosodium glutamate; MSG; Sodium glutamate
MDL No. :MFCD00013074

Safety of H-Glu-OH(Sodium)

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of H-Glu-OH(Sodium)

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 142-47-2 ]
  • Downstream synthetic route of [ 142-47-2 ]

[ 142-47-2 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 122-04-3 ]
  • [ 142-47-2 ]
  • [ 6758-40-3 ]
YieldReaction ConditionsOperation in experiment
29.81 g With sodium hydroxide In water at 0 - 20℃; for 1 h; In the reaction vessel, sodium glutamate 18.73g (0.11mol), water, 75g, stirring with 1mol / L aqueous sodium hydroxide solution of PH = 8, and slowly added dropwise at 0 28.31g step (1) of the resulting dichloroethane, nitrobenzene chloride solution, was dropwise added to 1mol / L aqueous sodium hydroxide to adjust the PH value of the reaction system was kept PH = 8, the reaction solution changed from white to purple discoloration, the addition was complete 1 hour reaction at room temperature, static layers were separated and the organic layer was extracted twice with water, the combined aqueous layer was acidified with hydrochloric PH = 1, the precipitated crystals were filtered and dried to give N- Nitrobenzoylhydrazone -L- glutamic acid 29.81 g, HPLC purity of 98.43percent, a yield of 99.03percent (with on-nitro benzoic acid).
References: [1] Patent: CN105439895, 2016, A, . Location in patent: Paragraph 0027; 0028.
 

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