Home Cart Sign in  
Chemical Structure| 917251-85-5 Chemical Structure| 917251-85-5

Structure of 917251-85-5

Chemical Structure| 917251-85-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 917251-85-5 ]

CAS No. :917251-85-5
Formula : C9H5BrIN
M.W : 333.95
SMILES Code : IC1=CC2=CC=CC(Br)=C2N=C1
MDL No. :MFCD09261261
InChI Key :JPJKDNAXYHDTSK-UHFFFAOYSA-N
Pubchem ID :52987895

Safety of [ 917251-85-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 917251-85-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 917251-85-5 ]

[ 917251-85-5 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 917251-85-5 ]
  • [ 81290-20-2 ]
  • [ 917251-86-6 ]
YieldReaction ConditionsOperation in experiment
A mixture of cuprous iodide (0.25 g) and potassium fluoride (0.077 g) was placed under a high vacuum and heated until the solid assumed a sight green color. The cooled solid mass was suspended in anhydrous N-methylpyrrolidinone (5 mL) and then treated with <strong>[917251-85-5]8-bromo-3-iodoquinoline</strong> (Step 1, 0.40 g), followed by trifluoromethyl-trimethylsilane (0.17 g). The resulting mixture was stirred at 50 C. for 18 hours. The mixture was then cooled to room temperature and poured into 15% aqueous NH4OH and then extracted with Et2O. The organic layer was washed with water and brine, dried over anhydrous Na2SO4, filtered and concentrated on a rotary evaporator. The crude product was purified by flash chromatography on silica gel using hexane/ethyl acetate to give 0.24 g of the desired product as a brown oil; MS (ES) m/z (relative intensity); 277 (M+H)+ (100).
  • 2
  • [ 16567-18-3 ]
  • [ 917251-85-5 ]
YieldReaction ConditionsOperation in experiment
With N-iodo-succinimide; In acetic acid; at 70℃; for 18.0h; To a solution of 8-bromoquinoline (commercially available, 1.0 g) in glacial acetic acid (6 mL) was added portionwise, N-iodosuccinimide (1.08 g). The resulting mixture was stirred at 70 C. for 18 hours. The reaction was cooled to room temperature and concentrated on a rotary evaporator. The residue was taken up in CH2Cl2 and washed with saturated aqueous NaHCO3 and brine. The organic layer was dried over anhydrous Na2SO4, filtered and concentrated on a rotary evaporator. The crude product was purified by flash chromatography on silica using hexane/ethyl acetate to give 0.74 g of the desired product as a white solid; MS (ES) m/z (relative intensity): 334 (M+H)+ (100).
  • 3
  • [ 917251-85-5 ]
  • [ 10112-11-5 ]
  • [ 917251-86-6 ]
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 917251-85-5 ]

Bromides

Chemical Structure| 1379316-32-1

A465319 [1379316-32-1]

3-Bromo-8-iodoquinoline

Similarity: 0.95

Chemical Structure| 1245563-17-0

A544868 [1245563-17-0]

8-Bromo-6-iodoquinoline

Similarity: 0.91

Chemical Structure| 205114-20-1

A208467 [205114-20-1]

3-Bromo-6-iodoquinoline

Similarity: 0.90

Chemical Structure| 1416440-23-7

A112821 [1416440-23-7]

6-Bromo-3-iodoquinoline

Similarity: 0.90

Chemical Structure| 1221278-74-5

A553854 [1221278-74-5]

7-Bromo-3-iodo-1H-pyrrolo[3,2-c]pyridine

Similarity: 0.89

Iodides

Chemical Structure| 1379316-32-1

A465319 [1379316-32-1]

3-Bromo-8-iodoquinoline

Similarity: 0.95

Chemical Structure| 1245563-17-0

A544868 [1245563-17-0]

8-Bromo-6-iodoquinoline

Similarity: 0.91

Chemical Structure| 205114-20-1

A208467 [205114-20-1]

3-Bromo-6-iodoquinoline

Similarity: 0.90

Chemical Structure| 1416440-23-7

A112821 [1416440-23-7]

6-Bromo-3-iodoquinoline

Similarity: 0.90

Chemical Structure| 1221278-74-5

A553854 [1221278-74-5]

7-Bromo-3-iodo-1H-pyrrolo[3,2-c]pyridine

Similarity: 0.89

Related Parent Nucleus of
[ 917251-85-5 ]

Quinolines

Chemical Structure| 1379316-32-1

A465319 [1379316-32-1]

3-Bromo-8-iodoquinoline

Similarity: 0.95

Chemical Structure| 1245563-17-0

A544868 [1245563-17-0]

8-Bromo-6-iodoquinoline

Similarity: 0.91

Chemical Structure| 205114-20-1

A208467 [205114-20-1]

3-Bromo-6-iodoquinoline

Similarity: 0.90

Chemical Structure| 1416440-23-7

A112821 [1416440-23-7]

6-Bromo-3-iodoquinoline

Similarity: 0.90

Chemical Structure| 1354223-46-3

A149679 [1354223-46-3]

3-Bromo-7-iodoquinoline

Similarity: 0.88